Dr Caroline Smith

Senior Lecturer

+44 20 7911 5000 ext 64119
115 New Cavendish Street London W1W 6UW
Mondays 1.15-2.30pm, please email to arrange to see me at other times

I'm part of

Life Sciences | Department

I am Course Leader for the Biological Sciences program and Learning and Teaching Coordinator for the Department of Life Sciences. I am a Senior Fellow of the Higher Education Academy, I have an MA in Higher Education awarded by University of Westminster and I am a University of Westminster Teaching Fellow.

I am a Senior Lecturer in Biochemistry and lead modules in Molecular Biology. My undergraduate degree was in Medical Biochemistry (University of Surrey) and I studied for a collaborative PhD at Cornell University Medical College which was awarded by University of Surrey. I worked as a post-doctoral Research Fellow on a British Heart Foundation program grant at University College London for almost five years before starting at University of Westminster in 2005. I am the Local Ambassador for the Biochemical Society.

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My introduction to teaching was at the University College London where I was a tutor in the Medical School for a couple of years. Since joining University of Westminster I completed the Certificate of Higher Education (2007) becoming a Fellow of the HEA in 2008 and a Senior Fellow in 2015. I was awarded an MA in Higher Education by University of Westminster in October 2015. I am currently the Departmental Learning and teaching Coordinator and represent our Department at the Faculty Learning and Teaching Committee.

I was awarded a University of Westminster Teaching Fellowship in 2016.

I am the course leader for the Biological Science subjects (including the biotechnology, cancer biology, forensic biology, microbiology and molecular biology and genetics pathways). I am an academic personal tutor with experience of having been Senior Tutor. I currently lead the Level 5 Molecular Biology and Genetics module and level 6 DNA in Identity and Disease. I contribute teaching in biochemistry, cell signalling and molecular biology areas to a variety of undergraduate modules including Cancer Biology, Techniques in Forensic Biology, Molecular Therapeutics and Applications in Molecular and Applied Biosciences.

At postgraduate level I contribute to teaching in Drug Discovery and Clinical Chemistry. I have always believed that research should inform teaching and I supervise undergraduate and postgraduate research projects. I am currently Director of Studies  PhD supervisor for Nasrin Nuri A. Berruien, and I am actively involved with the Graduate Centre as an MPhil and PhD Chair and examiner.

Following on from a degree in Medical Biochemistry, during which I spent a fascinating Sandwich year working with Dr Steven Gross at Cornell University Medical College looking at the calcium and calmodulin regulation of nitric oxide synthases; I went back to New York to research transcriptional regulation of the GTP cyclohydrolase gene, which encodes for an important enzyme in tetrahydrobiopterin biosynthesis, an essential cofactor for the production of tyrosine, catecholamines and serotonin, as well as Nitric Oxide.

My PhD thesis "Pterin biosynthesis, binding and modulation of eNOS catalytic function" was examined and awarded by University of Surrey. As a post-doctoral research fellow at UCL I worked with Prof Patrick Vallance researching the pathophysiological effects of asymmetric dimethylarginine on the cardiovasculature. I am still interested how novel compounds can contribute to the control of this molecule.

University of Westminster has broadened my research horizons taking techniques I had expertise in and applying them to new areas. This is how I developed collaborations with KNUST, Kumasi Ghana through a project looking at how the incidence of malaria is influenced by alpha-thalassemia genotype and became interested in melanocortin signalling in the reproductive axis and the roles of cancer stem cells in osteosarcoma.

My main research interest remains with the endothelial cell biology within the cardiovascular system and I have worked on projects including investigating the effects of thiol isomerases on endothelial activation with Dr Gordge. I collaborate with my colleague Prof Ipsita Roy and combining knowledge of mammalian cells with polyhydroxyalkanoates for medical applications.

I’m delighted to have contributed to the doctoral supervision of these talented scientists:

Opoku-Okrah, Clement (2012) An investigation of the protective effect of alpha+-thalassaemia against severe Plasmodium falciparum amongst children in Kumasi, Ghana.

Basnett, Pooja (2014) Biosynthesis of polyhydroxyalkanoates, their novel blends and composites for biomedical applications.

Dowejko, Monika (2014) Characterization of MC3 and the other melancortin receptors (MC) in the hypothalamo-pituitary-gonadal system of the mouse.

Jenks, Andrew (2014) The role of cancer stem cells in osteosarcoma.

Most of my research fits within the Cell Communication Research Group, and I am our appointed tweeter (follow us @Cell_Comm_Group) but I support the Education Research group and collaborate with the Applied Biotechnology and Cancer Research Groups. I am the University of Westminster Local Ambassador for the Biochemical Society which exists to advance the molecular and cellular biosciences.

I am currently collaborating with Dr Sharron Rossiter, University of Hertfordshire, Dr Joanne Murray, University of Edinburgh and Dr Ian Bailey, University of Surrey, in addition to the prior-mentioned investigators. I have received funding from the Biochemical Society, Nuffield Society and joint funding with Drs Murray and Getting from Society for Endocrinology.

In 2016 we were recently awarded £915 Practical Skills Grant from Society of Endocrinology https://www.endocrinology.org/ for Nasrin Berruien (2nd Year PhD student) to learn a novel Protein-Fragment complementation Assay at University of Edinburgh to investigate the potential cross talk between Adrenocorticotropic hormone (ACTH) and ghrelin within the gonadotrophs and the somatotrophs

In 2017 £400 Biochemical Society sponsored Events Grant Scheme for the University of Westminster iGEM (International Genetically Engineered Machine) team to host a 1 day UK meet up on Friday 17th August 2017.

British Pharmacological Society bursary to attend and present poster "In silico and in vitro approaches to develop Dimethylarginine dimethylaminohydrolase-1 inhibitors". At  "In silico and in vitro methods in modern drug discovery", University of Nottingham 24-25th April 2017

2017

Using virtual reality to prepare Bioscience students for practical classes (2017)
Coleman, S.K., Volpi, E. and Smith, C.L. 2017. Using virtual reality to prepare Bioscience students for practical classes. 16th Westminster Symposium Innovate!. University of Westminster, London 22 to end of 22 Jun 2017
Increasing accessibility of students to laboratory classes through the use of Virtual laboratory simulations (2017)
Smith, C.L. and Coleman, S.K. 2017. Increasing accessibility of students to laboratory classes through the use of Virtual laboratory simulations . UALL Work and Learning Network Annual Conference 2017 - Leading the Way: Shaping Practice in the Workplace and the Academy.. Middlesex University 23 to end of 23 Jun 2017
Using Labster to improve Bioscience student learning and engagement in practical classes (2017)
Smith, C.L. and Coleman, S.K. 2017. Using Labster to improve Bioscience student learning and engagement in practical classes. Heads of Biological Sciences, Royal Society of Biology. Spring 2017 meeting.. University of Leicester 10 to end of 11 May 2017
In silico and in vitro approaches to develop Dimethylarginine dimethylaminohydrolase-1 inhibitors (2017)
Smith, C.L., Zloh, M. and Rossiter, S. 2017. In silico and in vitro approaches to develop Dimethylarginine dimethylaminohydrolase-1 inhibitors. Kendall, D. (ed.) In silico and in vitro methods in modern drug discovery. University of Nottingham 24 to end of 25 Apr 2017 British Pharmacological Society.

2016

Effect of age and pregnancy on the expression of melanocortin receptors 4 and 5 in the mouse female reproductive axis (2016)
Smith, C.L., Nuri A. Berruien, N., Murray, J.F. and Le Tissier, P.R. 2016. Effect of age and pregnancy on the expression of melanocortin receptors 4 and 5 in the mouse female reproductive axis. BPS Pharmacology 2016. London, UK 12 to end of 14 Dec 2016 British Pharmacological Society.
Next generation e-learning platform: virtual laboratory simulations (2016)
Smith, C.L. and Markiv, A. 2016. Next generation e-learning platform: virtual laboratory simulations. Heads of Biological Sciences, Royal Society of Biology, Spring 2016. University of Leicester 04 to end of 05 May 2016
An investigation into the impact of peer- and self-marking in a first year biochemistry module (2016)
Smith, C.L. 2016. An investigation into the impact of peer- and self-marking in a first year biochemistry module. Inspire to succeed: Transforming teaching and learning in STEM. East Midlands Conference Centre, Nottingham on 28 and 29 January 2016 28 Jan 2016

2015

Curriculum and beyond: Mathematics support for first year life science students (2015)
Bailey, I., Ferrier, C. and Smith, C.L. 2015. Curriculum and beyond: Mathematics support for first year life science students. CETL-MSOR Conference 2015. University of Greenwich 08 Sep 2015 The Sigma Network.

2014

Melanocortin receptor expression in the hypothalamo-pituitary-gonadal system of WT and MC3 null mice (2014)
Dowejko, M.M., Smith, C.L., Getting, S.J., Le Tissier, P. and Murray, J.F. 2014. Melanocortin receptor expression in the hypothalamo-pituitary-gonadal system of WT and MC3 null mice. International Congress of Neuroendocrinology 2014. Sydney 17-20 August 2014
Melanocortin 3 receptors (MC3) exert anti-inflammatory effects in mouse testicular inflammation by reducing nitric oxide (NO) release from Leydig cells (2014)
Dowejko, M.M., Smith, C.L., Getting, S.J., Le Tissier, P. and Murray, J.F. 2014. Melanocortin 3 receptors (MC3) exert anti-inflammatory effects in mouse testicular inflammation by reducing nitric oxide (NO) release from Leydig cells. Society for Reproduction and Fertility Conference. EICC2, Edinburgh 1-2 September 2014

2013

The role of cancer stem cells in osteosarcoma (2013)
Jenks, A., Smith, C.L., Patel, V. and Clements, M.O. 2013. The role of cancer stem cells in osteosarcoma. International society for stem cell research conference. Boston (Massachusetts, USA) June 12 – 15 2013
Melanocortin 3 receptor (MC3) activation effects on testicular testosterone and nitrite production in vitro (2013)
Dowejko, M.M., Smith, C.L., Getting, S.J., Le Tissier, P. and Murray, J.F. 2013. Melanocortin 3 receptor (MC3) activation effects on testicular testosterone and nitrite production in vitro. Society for Reproduction and Fertility (SRF) Annual Conference. Cambridge 11th July 2013
Recovery of DNA from coloured fabrics: a study into the effects of clothing dye contamination on the recovery and amplification of DNA (2013)
Bux, U., Mubarakku, S., Bennett-Cadette, C. and Smith, C.L. 2013. Recovery of DNA from coloured fabrics: a study into the effects of clothing dye contamination on the recovery and amplification of DNA. 9th National FORREST Conference 2013 (FORensic RESearch and Teaching). Anglia Ruskin University 25-26th June 2013

2012

Expression of melanocortin 3 receptors (MC3) in the reproductive axes of both male and female mice (2012)
Dowejko, M.M., Smith, C.L., Getting, S.J., Le Tissier, P. and Murray, J.F. 2012. Expression of melanocortin 3 receptors (MC3) in the reproductive axes of both male and female mice. Society for Reproduction and Fertility. Edinburgh 9th - 11th July 2012
Alpha thalassaemia and the severity of Plasmodium falciparum infection in microcytic children from the Ashanti region of Ghana (2012)
Opoku-Okrah, C., Smith, C.L., Gordge, M.P., Parry, M., Robertson, C.E., Abgenyega, T. and Nakua, E. 2012. Alpha thalassaemia and the severity of Plasmodium falciparum infection in microcytic children from the Ashanti region of Ghana. British Society for Haematology 52nd meeting. Glasgow 16-18 April 2012

2011

Polyhydroxyalkanoate (PHA): bacterial cellulose composites for biomedical applications (2011)
Basnett, P., Smith, C.L., Boccaccini, A.R., Knowles, J.C., Keshavarz, T. and Roy, I. 2011. Polyhydroxyalkanoate (PHA): bacterial cellulose composites for biomedical applications. European Society of Biomaterials. Dublin, Ireland Sept 2011
Total pituitary hormone content in wild type and MC3 null male and female mice (2011)
Dowejko, M.M., Smith, C.L., Getting, S.J., Perretti, M., Le Tissier, P. and Murray, J.F. 2011. Total pituitary hormone content in wild type and MC3 null male and female mice. British Society for Neuroendocrinology. Cambridge 3rd - 5th July 2011
Comparison between the total pituitary hormone content in wild type and melanocortin 3 receptor (MC3) null male and female mice (2011)
Dowejko, M.M., Smith, C.L., Getting, S.J., Perretti, M., Le Tissier, P. and Murray, J.F. 2011. Comparison between the total pituitary hormone content in wild type and melanocortin 3 receptor (MC3) null male and female mice. Society for Reproduction and Fertility. Brighton 11th - 13th July 2011

2010

Activation of testicular melanocortin 3 receptors (MC3-R) inhibits LH-stimulated testosterone production (2010)
Akindele, K., Horanin, M.M., Getting, S.J., Smith, C.L. and Murray, J.F. 2010. Activation of testicular melanocortin 3 receptors (MC3-R) inhibits LH-stimulated testosterone production. Society for Endocrinology BES 2010. Manchester 15th - 18th March 2010
Testicular LH-stimulated testosterone production is inhibited by activation of melanocortin 3 receptors (MC3) (2010)
Akindele, K., Horanin, M.M., Getting, S.J., Smith, C.L. and Murray, J.F. 2010. Testicular LH-stimulated testosterone production is inhibited by activation of melanocortin 3 receptors (MC3). Society for Reproduction and Fertility. Sutton Bonnington 11th - 13th July 2010

2008

Melanocortin 3 receptor in the testes of mice (2008)
Yogarajah, S., Lynch, S., Smith, C.L., Getting, S.J., Perretti, M. and Murray, J.F. 2008. Melanocortin 3 receptor in the testes of mice. Society for Reproduction and Fertility. Edinburgh 29 Jun - 01 Jul 2008 pp. Abstract P80

2005

Dimethylarginine dimethylaminohydrolase I (DDAH I) heterozygous knockout mice display a cardiovascular phenotype consisting of pulmonary and systemic endothelial dysfunction (2005)
Malaki, M., Nandi, M., Madhani, M., Gill, H., Smith, C.L., Leiper, J.M. and Vallance, P. 2005. Dimethylarginine dimethylaminohydrolase I (DDAH I) heterozygous knockout mice display a cardiovascular phenotype consisting of pulmonary and systemic endothelial dysfunction. British Pharmaceutical Society Summer Meeting. Cambridge, UK 06-08 Jul 2005

2004

Effects of low dose ADMA on gene expression in human coronary artery endothelial cells (2004)
Smith, C.L., Leiper, J.M. and Vallance, P. 2004. Effects of low dose ADMA on gene expression in human coronary artery endothelial cells. 3rd International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide: 4th Anuual Scientific Meeting of the Nitric Oxide Society of Japan. Nara, Japan 24-28 May 2004
Restoration of nitric oxide production by N-hydroxyarginine in endothelial cells with NO deficiency triggered by elevated glucose (2004)
Crabtree, M.J., Smith, C.L. and Gross, S.S. 2004. Restoration of nitric oxide production by N-hydroxyarginine in endothelial cells with NO deficiency triggered by elevated glucose. 3rd International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide: 4th Anuual Scientific Meeting of the Nitric Oxide Society of Japan. Nara, Japan 24-28 May 2004

2015

Inhibition of thiol isomerase activity diminishes endothelial activation of plasminogen, but not of protein C (2015)
Smith, C.L., Shah, C.M., Kamaludin, N. and Gordge, M.P. 2015. Inhibition of thiol isomerase activity diminishes endothelial activation of plasminogen, but not of protein C. Thrombosis Research. 135 (4), p. 748–753.

2014

An investigation of the protective effect of alpha+-thalassaemia against severe Plasmodium falciparum amongst children in Kumasi, Ghana (2014)
Opoku-Okrah, C., Gordge, M.P., Kweku Nakua, E., Abgenyega, T., Parry, M., Robertson, C.E. and Smith, C.L. 2014. An investigation of the protective effect of alpha+-thalassaemia against severe Plasmodium falciparum amongst children in Kumasi, Ghana. International Journal of Laboratory Haematology. 36 (1), pp. 62-70.
The melanocortin system in the male reproductive axis (2014)
Dowejko, M.M., Smith, C.L., Getting, S.J., Le Tissier, P. and Murray, J.F. 2014. The melanocortin system in the male reproductive axis. Endocrine Abstracts. 34, p. P338.

2013

Novel Poly(3-hydroxyoctanoate)/Poly(3-hydroxybutyrate) blends for medical applications (2013)
Basnett, P., Ching, K.Y., Stolz, M., Knowles, J.C., Boccaccini, A.R., Smith, C.L., Locke, I.C., Keshavarz, T. and Roy, I. 2013. Novel Poly(3-hydroxyoctanoate)/Poly(3-hydroxybutyrate) blends for medical applications. Reactive and Functional Polymers. 73 (10), pp. 1340-1348.
Aspirin-loaded P(3HO)/P(3HB) blend films: potential materials for biodegradable drug-eluting stents (2013)
Basnett, P., Ching, K.Y., Stolz, M., Knowles, J.C., Boccaccini, A.R., Smith, C.L., Locke, I.C. and Roy, I. 2013. Aspirin-loaded P(3HO)/P(3HB) blend films: potential materials for biodegradable drug-eluting stents. Bioinspired, Biomimetic and Nanobiomaterials. 2 (3), pp. 141-153.

2012

Novel biodegradable and biocompatible poly(3-hydroxyoctanoate)/bacterial cellulose composites (2012)
Basnett, P., Knowles, J.C., Pishbin, F., Smith, C.L., Keshavarz, T., Boccaccini, A.R. and Roy, I. 2012. Novel biodegradable and biocompatible poly(3-hydroxyoctanoate)/bacterial cellulose composites. Advanced Engineering Materials. 14 (6), pp. B330-B343.
A comparison of novel NG, NG-disubstituted arginines on recombinant dimethylarginine dimethylaminohydrolase-1 activity and nitrite production in RAW264.7 macrophages (2012)
Morfill, C., Rossiter, S. and Smith, C.L. 2012. A comparison of novel NG, NG-disubstituted arginines on recombinant dimethylarginine dimethylaminohydrolase-1 activity and nitrite production in RAW264.7 macrophages. Proceedings of the British Pharmacological Society. 10 (4).

2009

Molecular characterization of the melanocortin 3 receptor in the testes of mice (2009)
Horanin, M.M., Akindele, K., Getting, S.J., Smith, C.L. and Murray, J.F. 2009. Molecular characterization of the melanocortin 3 receptor in the testes of mice. pA2 Online. From the Queen Elizabeth II Conference Centre London, Winter 2009 Meeting: Proceedings of the British Pharmacological Society. 7 (4).

2008

Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. Superoxide production by eNOS (2008)
Crabtree, M.J., Smith, C.L., Lam, G., Goligorsky, M.S. and Gross, S.S. 2008. Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. Superoxide production by eNOS. American Journal of Physiology: Heart and Circulatory Physiology. 294 (4), pp. H1530-H1540.
Melanocortin 3 receptor in the testes of mice (2008)
Wotherspoon, G., Yogarajah, S., Lynch, S., Smith, C.L., Getting, S.J., Perretti, M. and Murray, J.F. 2008. Melanocortin 3 receptor in the testes of mice. pA2 Online. From the University of Brighton, Winter 2008 Meeting: Proceedings of the British Pharmacological Society. 6 (4), p. P008.
Asymmetric dimethylarginine negatively influences osteoblast differentiation in vitro (2008)
Stenbeck, G., Joseph, J., Getting, S.J. and Smith, C.L. 2008. Asymmetric dimethylarginine negatively influences osteoblast differentiation in vitro. pA2 Online. From the University of Brighton, Winter 2008 Meeting: Proceedings of the British Pharmacological Society. 6 (4), p. C041.

2007

Disruption of methylarginine metabolism impairs vascular homeostasis (2007)
Leiper, J.M., Nandi, M., Torondel, B., Murray-Rust, J., Malaki, M., O'Hara, B., Rossiter, S., Anthony, S., Madhani, M., Selwood, D.L., Smith, C.L., Wojciak-Stothard, B., Rudiger, A., Stidwill, R., McDonald, N.Q. and Vallance, P. 2007. Disruption of methylarginine metabolism impairs vascular homeostasis. Nature Medicine. 13 (2), pp. 198-203.
C-reactive protein and asymmetric dimethylarginine: markers or mediators in cardiovascular disorders? (2007)
Smith, C.L. 2007. C-reactive protein and asymmetric dimethylarginine: markers or mediators in cardiovascular disorders? Current Pharmaceutical Design. 13 (16), pp. 1619-1629.

2005

Effects of ADMA upon gene expression: an insight into the pathophysiological significance of raised plasma ADMA (2005)
Smith, C.L., Anthony, S., Hubank, M., Leiper, J.M. and Vallance, P. 2005. Effects of ADMA upon gene expression: an insight into the pathophysiological significance of raised plasma ADMA. PLoS Medicine. 2 (10), pp. 1031-1043.
Cardiovascular tests: use & limits of biochemical markers - therapeutic measurements of ADMA involved in cardiovascular disorders (2005)
Smith, C.L. and Vallance, P. 2005. Cardiovascular tests: use & limits of biochemical markers - therapeutic measurements of ADMA involved in cardiovascular disorders. Current Pharmaceutical Design. 11 (17), pp. 2177-2185.
Selective substrate-based inhibitors of mammalian dimethylarginine dimethylaminohydrolase (2005)
Rossiter, S., Smith, C.L., Malaki, M., Nandi, M., Gill, H., Leiper, J.M., Vallance, P. and Selwood, D.L. 2005. Selective substrate-based inhibitors of mammalian dimethylarginine dimethylaminohydrolase. Journal of Medicinal Chemistry. 48 (14), pp. 1670-1678.

2004

Effects of low dose ADMA on gene expression in human coronary artery endothelial cells (2004)
Smith, C.L., Leiper, J.M. and Vallance, P. 2004. Effects of low dose ADMA on gene expression in human coronary artery endothelial cells. Nitric Oxide: Biology and Chemistry. 11 (1), p. 59.
Restoration of nitric oxide production by N-hydroxy-L-arginine in endothelial cells with NO deficiency triggered by elevated glucose (2004)
Crabtree, M.J., Smith, C.L. and Gross, S.S. 2004. Restoration of nitric oxide production by N-hydroxy-L-arginine in endothelial cells with NO deficiency triggered by elevated glucose. Nitric Oxide: Biology and Chemistry. 11 (1), p. 65.

2003

Dimethylarginine dimethylaminohydrolase activity modulates ADMA levels, VEGF expression, and cell phenotype (2003)
Smith, C.L., Birdsey, G.M., Anthony, S., Arrigoni, F.I., Leiper, J.M. and Vallance, P. 2003. Dimethylarginine dimethylaminohydrolase activity modulates ADMA levels, VEGF expression, and cell phenotype. Biochemical and Biophysical Research Communications. 308 (4), pp. 984-989.

2002

Activation and inactivation of neuronal nitric oxide synthase: characterization of Ca2+-dependent [125I]Calmodulin binding (2002)
Weissman, B.A., Jones, C.L., Liu, Q., Gross, S.S. and Smith, C.L. 2002. Activation and inactivation of neuronal nitric oxide synthase: characterization of Ca2+-dependent [125I]Calmodulin binding. European Journal of Pharmacology. 435 (1), pp. 9-18.

1997

An autoinhibitory control element defines calcium-regulated isoforms of nitric oxide synthase (1997)
Salerno, J.C., Harris, D.E., Irizarry, K., Patel, B., Morales, A.J., Smith, S.M.E., Martasek, P., Roman, L.J., Masters, B.S.S., Jones, C.L., Weissman, B.A., Lane, P., Liu, Q., Gross, S.S. and Smith, C.L. 1997. An autoinhibitory control element defines calcium-regulated isoforms of nitric oxide synthase. Journal of Biological Chemistry. 272 (47), pp. 29769-29777.

2009

Utilising mitochondrial DNA markers to identify insects for forensic applications: an investigation into how the preservation and storage of insect tissue can affect mtDNA yield (2009)
Thompson, A., Tinworth, L. and Smith, C.L. 2009. Utilising mitochondrial DNA markers to identify insects for forensic applications: an investigation into how the preservation and storage of insect tissue can affect mtDNA yield. in: Proceedings of the 5th National FORREST Conference 2009 (FORensic RESearch and Teaching), 30th June – 1st July 2009, Liverpool John Moores University Forensic Institute Research Network and The Higher Education Academy Physical Sciences Centre. pp. 45

2005

Pathophysiological concentrations of ADMA alter human coronary artery endothelial cell gene expression: an insight into the pathophysiological significance of raised plasma ADMA levels (2005)
Smith, C.L., Anthony, S., Malaki, M., Hubank, M., Leiper, J.M. and Vallance, P. 2005. Pathophysiological concentrations of ADMA alter human coronary artery endothelial cell gene expression: an insight into the pathophysiological significance of raised plasma ADMA levels. in: Boger, R., Fleming, I. and Waltenberger, J. (ed.) Vascular Biology and Medicine: 3rd European Meeting, Hamburg, September 2005, abstracts Germany Karger.
Potential therapeutic benefit of novel DDAH inhibitors for the treatment of endotoxemia (2005)
Nandi, M., Rossiter, S., Torondel, B., Malaki, M., Smith, C.L., Stidwill, R., Leiper, J.M. and Vallance, P. 2005. Potential therapeutic benefit of novel DDAH inhibitors for the treatment of endotoxemia. in: Boger, R., Fleming, I. and Waltenberger, J. (ed.) Vascular Biology and Medicine: 3rd European Meeting, Hamburg, September 2005, abstracts Germany Karger.
Evidence of systemic and pulmonary endothelial dysfunction in the Dimethylarginine Dimethylaminohydrolase I (DDAH I+/-) heterozygous knockout mouse (2005)
Malaki, M., Nandi, M., Madhani, M., Gill, H., Smith, C.L., Leiper, J.M. and Vallance, P. 2005. Evidence of systemic and pulmonary endothelial dysfunction in the Dimethylarginine Dimethylaminohydrolase I (DDAH I+/-) heterozygous knockout mouse. in: Boger, R., Fleming, I. and Waltenberger, J. (ed.) Vascular Biology and Medicine: 3rd European Meeting, Hamburg, September 2005, abstracts Germany Karger.

2002

The redox status of bound pterin cofactor determines whether eNOS produces NO or superoxide anion: [3H] - BH4 binding studies provide insights into vascular pathophysiology (2002)
Jones, C.L., Vasquez-Vivar, J., Kalyanaraman, B., Griscavage-Ennis, J.M., Gross, S.S. and Smith, C.L. 2002. The redox status of bound pterin cofactor determines whether eNOS produces NO or superoxide anion: [3H] - BH4 binding studies provide insights into vascular pathophysiology. in: Milstien, S., Kapatos, G., Levine, R.A. and Shane, B. (ed.) Chemistry and biology of pteridines and folates: proceedings of the 12th International Symposium on Pteridines and Folates, National Institutes of Health, Bethesda, M.D. Boston, USA Kluwer Academic Publishers. pp. 271-276

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