All tissue undergoes constant remodelling to maintain architecture during growth, in normal physiology and in response to disease. The group’s research focus is to uncover novel pathways contributing to tissue remodelling and regeneration for maintenance of tissue architecture in response to both physiological and pathophysiological stimuli. The group fosters a multidisciplinary approach of original and translational research spanning immunology, genetics, cancer, stem cells, ageing and regenerative medicine.
Find out about the projects that the group has been involved in.
- Kosgodage U, Mould R, Henley A, Nunn AVW., Guy GW, Thomas EL, Inal JM, Bell JD and Lange S. 2018. Cannabidiol (CBD) is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer. Frontiers in Pharmacology. 9, p. 889.
- Magnadóttir B, Hayes P, Hristova M, Bragason BÞ, Nicholas AP, Dodds AW, Guðmundsdóttir S, Lange S. (2018). Post-translational Protein Deimination in Cod (Gadus morhua L.) Ontogeny: Novel Roles in Tissue Remodelling and Mucosal Immune Defences? Dev Comp Immunol. pii: S0145-305X(18)30082-X. doi: 10.1016/j.dci.2018.06.006. [Epub ahead of print].
- Magnadóttir B, Hayes P, Gísladóttir B, Bragason BÞ, Hristova M, Nicholas AP, Guðmundsdóttir S, Lange S. (2018). Pentraxins CRP-I and CRP-II are post-translationally deiminated and differ in tissue specificity in cod (Gadus morhua L.) ontogeny. Dev Comp Immunol. 87:1-11. doi: 10.1016/j.dci.2018.05.014.
Find out more about our academic staff and details of our research outputs.
Tissue Architecture and Regeneration Research Group, Cavendish Campus, 115 New Cavendish Street, London W1W 6UW
Contact Dr Sigrun Lange, Group Leader:
T: +44 (0)207 911 5000 ext 64832
E: [email protected]