Previous team members
Dr Babak Afrough
Babak read a PhD at the University of Westminster with Dr Pamela Greenwell, he has a background in protein biochemistry and analysis of mucin glycoproteins. Babak has evaluated lectin-arrays as a tool for assessing glycosylation of breast cancer tissues samples.
Babak’s work in the ABC Research Unit encompassed the analysis of IgG and IgM antibodies of cancer patients against Tn-antigen (a-GalNAc- Ser/Thr) and other cancer-associated O-glycosylated peptides. Babek is now working at Public Health England.
Simon is a glycobiologist with a background in biochemistry. Simon read his BSc at Imperial College London, and undertook post graduate work in the Department of Biochemistry, Oxford University. Simon has experience of glycan mapping using HPLC and MS, affinity chromatography and 2-DE based proteomics.
Simon is focussing on identification of proteins elevated in the serum of cancer patients using samples from the biobank established by Dr Leathem, shown above.
Amber joined the Diet and Lifestyle team in November 2011. She was involved in data entry and checking and liaison with Centres involved in the study. She was also responsible for preparation and despatch of all study consumables and monitoring stock levels.
Sally's background is in information and data; she joined the Diet and Lifestyle team in July 2011 from the University of London Computer Centre, where she was involved in digital preservation / archiving of government datasets. Her role now is entry of study data, data quality and checking, and liaison with Centres involved in the study, for example to follow-up on data anomalies and missing questionnaires etc.
Andy focussed on PSA and CEA glycosylation by establishing an ELISA method to enable analysis of these serum proteins with lectins.
Andy is now reading a PhD in the Department of Molecular and Applied Biosciences, University of Westminster, in the area of cancer stem cell biology.
Dr Hannah Lomax-Browne
Hannah studied at Oxford Brookes University, her PhD focussed on cancer-endothelial cell interactions (under Dr Susan Brooks). Hannah is a Fellow of the Royal Microscopical Society.
Hannah’s work in the ABC Research Unit focussed on changes in glycosylation of IgA1 in the serum of breast cancer patients and in breast cancer tissue samples.
Hannah is now working as a Post-Doctoral Researcher in the Centre for Complement & Inflammation Research (CCIR), Imperial College London.
PhD: “Identification, cloning and functional characterisation of lectins from the albumen gland of the Roman snail Helix pomatia”.
Anatoliy has been appointed Lecturer in the Department of Biomedical Sciences, University of Westminster, his research interest remain in the area of antibody engineering, cell imagine, glycobiology and bioinformatics.
Annie designed and maintained the DietCompLyf study databases (Access and MySQL).
She was involved in data extraction and analysis as well as collecting samples from patients enrolled in the study at the Whittington and University College Hospitals, part of the UCLHT.
PhD “Identification of tumour-associated glycoproteins recognised by the lectin Helix pomatia in breast cancer”.
Neela adopted cell biology, confocal microscopy and proteomic techniques to evaluate the glycoproteins recognised by the lectin HPA in breast cancer. Neela is now working as a Post-Doctoral Researcher in the Drickamer Lab at Imperial College London.
PhD: “The role of glycosidases in breast cancer formation and degradation of the extracellular matrix”. Kushen examined the levels of glycosidases in breast cancer cells and found these work in a synergistic manner with proteases to aid cellular invasion through the extracellular matrix.
Kushen is Deputy Head of Immunology, in the Immunology Department, The Doctors’ Laboratory, London.
PhD: "Characterisation of the Helix pomatia agglutinin binding glycoproteins of colorectal cancer cell lines and tissue samples" Julien moved to Attana AG as a Postdoctoral Scientist after completing his PhD, he is now working as a Project Manager at Innotrac Diagnostics(Radiometer) Finland.
Dr Ruth Swann
Ruth’s background is laboratory-based cancer research. Her PhD focussed on the influence of the oestrous cycle on the radiation response of tumours, read at the University of Manchester with Professor Ian Stratford. Subsequently Ruth undertook post doctoral research at the Paterson Institute for Cancer Research and as a research scientist with Astrazenca.
Ruth is responsible for leading the DietCompLyf study, co-ordination of all aspects of the study, quality control of the data, sample storage and initiating sample analysis. Ruth is involved in starting up new collaborative studies and leads the team in all the aspects of the Diet and Lifestyle Research.