I am a Neurobiologist and PhD student studying at the University of Westminster. I attained my 1st in Biomedical Science (BSc) from King's College London in 2014. Between 2012-2013 I underwent an exchange year at the National University of Singapore, one of the highest ranking universities in Asia.
am interested in the role of inflammation in Alzheimer's disease (AD), the greatest cause of dementia in the world's aging population.
The pathological hallmarks of AD are well established. However, our understanding of the pathological processes which underlie the disease remains poor.
More recently, it has been suggested that chronic inflammation through the build up of amyloid beta (Aβ) looks to play a very important role in the neurodegenerative process in AD. The cells at the heart of this unwanted inflammatory response, microglia, are the resident macrophages of the central nervous system.
Microglia have specific receptors on their cell surface, including the formyl peptide receptor 2 (FPR2), an anti-inflammatory G-protein coupled receptor (GPCR). My research will focus on the use of selective FPR2 agonists to determine whether specific activation of this receptor contributes to the reduction of Aβ triggered inflammation in cellular models of AD.
I am hopeful that this novel research will help towards the identification of new anti-inflammatory treatments that can target the underlying pathology of this debilitating disease.