I'm part of

Life Sciences | Department

My expertise is in microbial biotechnology, natural biomaterials and their biomedical applications. My undergraduate degree is in Chemistry (St. Stephen's College, Delhi University, India) and MSc degree is in Biotechnology (Jawaharlal Nehru University, India). In both institutions I was ranked first in the University. I was awarded the prestigious Inlaks Scholarship and the Overseas Research Students Award to study for my Ph.D. at the University of Cambridge. During my time at Cambridge I was awarded the Churchill College Scholarship, the Lundgren Scholarship, Leche Trust Scholarship and the Cambridge University Philosophical Society Fellowship Award. I obtained my Ph.D. at the Department of Biochemistry, where I studied a B12-dependent enzyme, methylmalonyl-CoA mutase under the supervision of Professor Peter Leadlay FRS. My postdoctoral work was at the University of Minnesota, USA, at the Bioprocess Technology Institute, where I worked on fatty acid biosynthesis. I taught at the Indian Institute of Technology, Delhi, India, for four years as an Assistant Professor at the Department of Biochemical Engineering and Biotechnology. During this time I worked actively on the production of biodegradable polymers from Streptomyces. 

I have been at the University of Westminster since 2000 and lead the Applied Biotechnology Research Group. I have published over 100 papers in high impact factor journals such as Biomaterials, Biomacromolecules, Journal of Royal Society Interface and presented my work at numerous international conferences. My group is currently focussed on the production of novel polyhydroxyalkanoates (PHAs), a group of FDA-approved natural polymers and their characterisation. We have pioneered the production of PHAs from Gram positive bacteria which lack immunogenic properties and hence are excellent materials for medical applications. In addition, my group is involved in the application of PHAs in the area of hard tissue engineering (bone), soft tissue engineering (cardiac, nerve), wound healing and drug delivery. 

I am an editor of the Journal of Chemical Technology and Biotechnology (JCTB), International Journal of Tissue Engineering and was the special editor of an In Focus Issue of JCTB on Biodegradable polymers. I am on the BBSRC, NSERC, Canada, FWF, Austria and NSFC, China, ESF, MUIR grant-reviewing panels and am the Vice Chair, Biotechnology section, SCI, London, UK. My work has been funded by the EPSRC (EP/C515617) EU (SOPHIED, QUORUM), DuPont and WESTFOCUS, London. I am a member of the BHF Cardiovascular Regenerative Medicine Centre led by Imperial College London that recently received £2.5 million funding.

Awards, scholarships, professional recognition

  • Best Chemistry Undergraduate Student Award, St. Stephen's College, 1984, 1985, 1986
  • Professor Seshadri Prize for being the best candidate in the BSc (Hons) Chemistry, University of Delhi, 1986
  • Best Biotechnology Masters Student Award, Jawaharlal Nehru University, New Delhi, 1988
  • Overseas Research Studentship from the Committee of Vice Chancellors and Principals, UK, 1989-1991
  • The Inlaks Scholarship, India, for doctoral studies at Cambridge, 1989-1990
  • Churchill College Scholarship, University of Cambridge, UK, 1991
  • Lundgren Scholarship, University of Cambridge, UK, 1992
  • Leche Trust Scholarship, London, UK, 1992
  • Cambridge University Philosophical Society Fellowship Award, Cambridge, UK, 1992
  • Nominated member of the New York Academy of Sciences in recognition of research activities, 1997

Grants awarded

  • EU H2020, HyMedPoly (ITN/EID Application): Drug-Free Antibacterial Hybrid Biopolymers for Medical Applications Jan 2015-Dec 2017, Total Grant Amount: 3,500,000 Euros; University of Westminster share: 1,093,152 Euros (£866,094.) This is for an Academic-Industry collaborative PhD multi-institution training network. Role in the project: Scientific Coordinator Partners involved: LUCIDEON Ltd, UK; Politecnico di Torino, Italy; Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany; Vornia Limited, Ireland; University of Southampton, UK;Universitätsklinikum Knappschaftskrankenhaus Bochum, Germany; Tekniker, Spain; Eurescom, Germany; Fraunhofer Gesellschaft, Germany. 
  • EU FP7 NMP: Reinforced Bioresorbable Biomaterials for Therapeutic Drug Eluting Stents (ReBioStent), Jan 2013- Dec 2016, Total Grant: 4.6 million Euros, University of Westminster share, 548,473.00 Euros (£434,515) Role in the project: Scientific Coordinator Partners involved: LUCIDEON Ltd, UK; Politecnico di Torino, Italy; Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany; Vornia Limited, Ireland; University of Southampton, UK; Universitätsklinikum Knappschaftskrankenhaus Bochum, Germany; Foundacion Tekniker, Spain; Eurescom, Germany; Fraunhofer Gesellschaft, Germany, Arterius Limited, UK; Life and Device SRL and University of Cambridge, UK. 
  • EU FP7 NMP: Novel combination of biopolymers and manufacturing technologies for production of a peripheral nerve implant containing an internal aligned channels array (NEURIMP), Jan 2014- Dec 2017, Total Grant: 4.4 million Euros, University of Westminster share, 504,053 Euros (£396,986) Role in the project: Work Package Leader Partners involved: Vornia Limited, Ireland; Foundacion Tekniker, Spain; Histocell, Spain ; Contipro Pharma A.S., Czech Republic; University of Sheffield, UK; Hospital Nacional Paraplejicos de Toledo, Spain; Qserve® Consultancy B.V., Netherlands. 
  • Co-I in The British Heart Foundation Cardiovascular Regenerative Medicine Centre Grant, 2013-2016 PI: Professor Sian Harding , Imperial College London, UK, £2.5 million Partners involved: Others at Imperial College: Michael Schneider, Stuart Cook, Amanda Fisher, Jesus Gil, Cesare Terracciano, Julia Gorelik, Alex Lyon, Nadia Rosenthal, Molly Stevens and Mark Mercola University of Nottingham, UK: Chris Denning University of Glasgow, UK: Godfrey Smith UKE Hamburg, Germany: Thomas Eschenhagen. 
  • Co-I in Project Title: Self-lubricating Polymer-based Artificial Cartilage Replacement (SPACER), 10th Call of the NIHR i4i Product Development Award 2016-2018 (Passed first stage) Total Budget: My Budget: £299,998 Partners involved: University of Southampton, UK: Martin Brown (PI) Aurora Medical (Industry): Andy Taylor and Anne Roques. 
  • PI for Internship Funding from Saudi Aramco (one of the largest oil companies), 2013-2015, £25,000. The EUMINAfab grant for visiting and carrying out research in TEKNIKER Technology Centre, Spain, 2012. EUMINAfab is a European Research Infrastructure offering open access to state of the art of multimaterial micro and nanotechnologies repertoire, £2000
  • European Social Fund within the Kracow University of Technology development program-top quality teaching for the prospective Polish engineers; University of the 21st century. One of the main goals of the project was to increase the competence of didactic staff by organising training in the European leading Centres. Funded the visit of Dr. Katarzyna Gorazda from Kracow University of Technology, Faculty of Chemical Engineering and Technology, Kracow, Poland from May 2012-August 2012, £4000.
  • A PARK fund for a further step forward towards the commercialisation of a unique drug delivery technology for wet macular degeneration from WESTFOCUS, 2010, London, UK, £50,068
  • A Bacillus based biorefinery for production of biodegradable biopolymers using agricultural residue, 2009, a research development fund, supported by the by University of Westminster, UK, £15,000
  • A PARK fund for patent application from WESTFOCUS, London, UK, 2009 £15,000
  • Eluting biodegradable ocular lens, 2009 – A Commercial Appraisal Fund from WESTFOCUS, London, UK, £1500
  • Polyhydroxyalkanoate microsphere-based intraocular drug delivery for wet macular degeneration, 2008, supported by WESTMARC, University of Westminster, UK, £2000
  • The Production and Characterisation of MCL-Polyhydroxyalkanoates for Biomedical Applications, 2007, supported by the University of Westminster, UK, £15,000
  • “QUORUM” with Prof. T. Keshavarz (PI) supported by EC/ FP6: Proposal no. 032811, 2006-2009, Title: Discovering Quorum Sensing in industrially useful Fungi, a novel approach at molecular level for scaling-up in white biotech. £250,000
  • Novel PHA/Bioglass composites for soft-tissue and hard-tissue engineering scaffolds, 2004-2006, supported by the Engineering and Physical Science Research Council, UK (EPSRC), £110,000
  • “SOPHIED” with Prof. T. Keshavarz (PI) supported by EC/FP6: Proposal no. 505899-2, 2004-2008, Title: Novel sustainable bioprocesses for the European colour industries. £299,200
  • Microbial production of Polyhydroxyalkanoates, 2000-2002, New lecturer’s Grant supported by the University of Westminster, UK, £30,000. 
  • Polyhydroxyalkanoate biosynthesis in Strepomyces sp., 1997-1998, University Exploratory Grant supported by DuPont, Delaware, USA, £2000 Total Funding obtained: £5.3 million

My teaching career began at the Indian Institute of Technology, Delhi, India where I taught biochemistry and molecular biology to students enrolled for an MEng degree in Biochemical Engineering. I developed many new modules including Molecular Biology for Engineers; Biochemistry; Advanced Techniques in Biochemical Engineering; Protein Engineering and Current Topics in Biotechnology.

After joining the University in 2000 I was appointed as the Course Leader for BSc Biochemistry. In 2002 I was appointed the Course Leader for BSc Biotechnology in Medicine and later that of BSc Biotechnology. In 2008, I was appointed the Course Leader for MSc Applied Microbiology and Biotechnology. In the past few years that I have run the course we have recruited well and the quality of the students have also been very good. I have now initiated a Year Abroad Program in partnership with the Vellore Institute of Technology (VIT), India, where students will join MSc Applied Microbiology and Biotechnology after completion of their first year of a two year Master's program in Applied Microbiology or Biotechnology at VIT.

I am currently Module Leader for Introduction to Biochemical Engineering; Biological and Organic Chemistry and Current topics in Biochemistry and Molecular Biology.

I am external examiner for the Intercalated BSc Programme on Regenerative Medicine and Innovation Technology at King's College, London.

I enjoy teaching thoroughly and feel that this aspect of my role at the university helps nurture and train the future generation, indeed a great responsibility. Hence, I feel it is essential to deliver this to the best of my abilities.

Current Research

My group is currently focussed on the production of natural polymers of bacterial origin including polyhydroxyalkanoates (PHAs), bacterial cellulose and -Polyglutamic acid, with a particular emphasis on PHAs.

Polyhydroxyalkanoates are a group of FDA-approved natural polymers that are biodegradable and biocompatible. These can be used for both bulk applications and medical applications. In my group we have investigated the medical applications of these polymers. We have pioneered the production of PHAs from Gram positive bacteria which lack immunogenic properties and hence are excellent materials for medical applications. There are two types of PHAs, SCL-PHAs (monomer length C4-C5), generally brittle in nature and MCL-PHAs (monomer length C6-C16), elastomeric in nature. The two main organisms that we produce for the production of these polymers are, Bacillus cereus SPV (for SCL-PHAs) and Pseudomonas mendocina (for MCL-PHAs).

We are currently investigating the application of PHAs in the area of bone tissue engineering, cardiac and nerve tissue engineering, wound healing and controlled drug delivery. In the area of bone tissue engineering we have developed Poly(3-hydroxybutyrate, P(3HB) composites with Bioglass®, carbon nanotubes, bacterial cellulose and magnetic nanoparticles. These have been characterised extensively for their material properties, degradability and biocompatibility. For cardiac tissue engineering applications we have developed Poly(3-hydroxyoctanoate), P(3HO) patches with added growth factors, i.e., Vascular Endothelial Growth Factor (VEGF) and peptides (RGD peptides). In addition, these patches have been coated with P(3HO) fibres, leading to essential surface topography, enhancing biocompatibility. I am now part of a BHF Cardiovascular Regenerative Medicine Centre led by Professor Sian Harding at Imperial College London, where P(3HO) and other PHAs will be explored for the development of cardiac patches to support stem cell growth and differentiation in to cardiac muscle. For wound healing applications two types of patches have been created, compressed films containing P(3HB) microspheres with encapsulated tetracycline; P(3HO) films with nanoBioglass. The former exhibited excelled controlled delivery of tetracycline and biocompatibility and the latter has potential haemostatic properties.

Finally, in the area of controlled delivery we have explored the use of P(3HB) microspheres for the delivery of small molecules such as gentamycin and proteins including bovine serum albumin. In both cases highly controlled long term delivery has been achieved. Another major application for PHAs being investigated in my group are drug eluting biodegradable stents. We have explored the use of P(3HO)/bacterial cellulose composites and P(3HB)/P(3HO) blends for the development of such stents. Preliminary stent prototypes have been produced using P(3HB)/P(HO) blends.

I collaborate with a large number of groups including those led by Professor Aldo Boccaccini (University of Erlangen, Germany); Professor Sian Harding (Imperial College London); Professor Jonathan Knowles (University College London); Professor Mohan Edirisinghe (University College London); Dr. Sanjukta Deb (King College London); Professor Ruth Cameron (University of Cambridge); Professor Serena Best (University of Cambridge); Dr. Iban Quintana (Tekniker, Spain). Within the University of Westminster I collaborate with Professor Tajalli Keshavarz; Dr. Ian Locke; Dr. Mike Gordge and Dr. Caroline Smith.

2017

Highly elastomeric poly(3-hydroxyoctanoate) based natural polymer composite for enhanced keratinocyte regeneration (2017)
Rai, R., Roether, J.A., Knowles, J.C., Mordan, N., Salih, V., Locke, I.C., Gordge, M.P., McCormick, A., Mohn, D., Stark, W.J., Keshavarz, T., Boccaccini, A.R. and Roy, I. 2017. Highly elastomeric poly(3-hydroxyoctanoate) based natural polymer composite for enhanced keratinocyte regeneration. International Journal of Polymeric Materials and Polymeric Biomaterials . 66 (7), pp. 326-335.
Synthesis of graft copolymers based on hyaluronan and poly(3-hydroxyalkanoates) (2017)
Huerta-Angeles, G., Brandejsová, M., Nigmatullin, N., Kopecká, K., Vágnerová, H., Šmejkalová, D., Roy, I. and Velebný, V. 2017. Synthesis of graft copolymers based on hyaluronan and poly(3-hydroxyalkanoates). Carbohydrate Polymers. 171, pp. 220-228.
A Strategy for Dual Biopolymer Production of P(3HB) and γ-PGA (2017)
Sukan, A., Roy, I. and Keshavarz, T. 2017. A Strategy for Dual Biopolymer Production of P(3HB) and γ-PGA. Journal of Chemical Technology and Biotechnology. 92 (7), pp. 1548-1557.

2016

Poly(3-hydroxyoctanoate), a promising new material for cardiac tissue engineering (2016)
Bagdadi, A., Safari, M., Dubey, P., Basnett, P., Sofokleous P., Humphrey E, Locke, I.C., Edirisinghe M., Terracciano C., Boccaccini, A.R., Knowles, J.C., Harding, S. and Roy, I. 2016. Poly(3-hydroxyoctanoate), a promising new material for cardiac tissue engineering. Journal of Tissue Engineering and Regenerative Medicine.
Novel P(3HB) Composite Films Containing Bioactive Glass Nanoparticles for Wound Healing Applications (2016)
Francis, L., Meng, D., Locke, I.C., Knowles, J.C., Mordan, N., Salih, V., Boccaccini, A.R. and Roy, I. 2016. Novel P(3HB) Composite Films Containing Bioactive Glass Nanoparticles for Wound Healing Applications. Polymer International. 65 (6), pp. 661-674.

2015

Dual production of biopolymers from bacteria (2015)
Sukan, A., Roy, I. and Keshavarz, T. 2015. Dual production of biopolymers from bacteria. Carbohydrate Polymers. 126, pp. 47-51.

2014

Agro-Industrial Waste Materials as Substrates for the Production of Poly(3-Hydroxybutyric Acid) (2014)
Sukan, A., Roy, I. and Keshavarz, T. 2014. Agro-Industrial Waste Materials as Substrates for the Production of Poly(3-Hydroxybutyric Acid). Journal of Biomaterials and Nanobiotechnology. 5 (4), pp. 229-240.

2013

Composite polymer-bioceramic scaffolds with drug delivery capability for bone tissue engineering (2013)
Mourino, V., Cattalini, J.P., Roether, J.A., Dubey, P., Roy, I. and Boccaccini, A.R. 2013. Composite polymer-bioceramic scaffolds with drug delivery capability for bone tissue engineering. Expert Opinion on Drug Delivery. 10 (10), pp. 1353-1365.
Novel Poly(3-hydroxyoctanoate)/Poly(3-hydroxybutyrate) blends for medical applications (2013)
Basnett, P., Ching, K.Y., Stolz, M., Knowles, J.C., Boccaccini, A.R., Smith, C.L., Locke, I.C., Keshavarz, T. and Roy, I. 2013. Novel Poly(3-hydroxyoctanoate)/Poly(3-hydroxybutyrate) blends for medical applications. Reactive and Functional Polymers. 73 (10), pp. 1340-1348.
Evidence for the involvement of intracellular Ca 2+ ions in the elicitation mechanism of Bacillus Licheniformis (2013)
Reffatti, P., Roy, I., Odell, M. and Keshavarz, T. 2013. Evidence for the involvement of intracellular Ca 2+ ions in the elicitation mechanism of Bacillus Licheniformis. Journal of Molecular Microbiology and Biotechnology. OnlineFirst.
Aspirin-loaded P(3HO)/P(3HB) blend films: potential materials for biodegradable drug-eluting stents (2013)
Basnett, P., Ching, K.Y., Stolz, M., Knowles, J.C., Boccaccini, A.R., Smith, C.L., Locke, I.C. and Roy, I. 2013. Aspirin-loaded P(3HO)/P(3HB) blend films: potential materials for biodegradable drug-eluting stents. Bioinspired, Biomimetic and Nanobiomaterials. 2 (3), pp. 141-153.
Advances in PHAs Production (2013)
Amache, R., Sukan, A., Safari, M., Roy, I. and Keshavarz, T. 2013. Advances in PHAs Production . CHEMICAL ENGINEERING TRANSACTIONS. 32, pp. 931-936.
Tetracycline-encapsulated P(3HB) microsphere-coated 45S5 Bioglass®-based scaffolds for bone tissue engineering (2013)
Meng, D., Francis, L., Thompson, I.D., Mierke, C., Huebner, H., Amtmann, A., Roy, I. and Boccaccini, A.R. 2013. Tetracycline-encapsulated P(3HB) microsphere-coated 45S5 Bioglass®-based scaffolds for bone tissue engineering. Journal of Materials Science: Materials in Medicine. 24 (12), pp. 2809-2817.

2012

Novel biodegradable and biocompatible poly(3-hydroxyoctanoate)/bacterial cellulose composites (2012)
Basnett, P., Knowles, J.C., Pishbin, F., Smith, C.L., Keshavarz, T., Boccaccini, A.R. and Roy, I. 2012. Novel biodegradable and biocompatible poly(3-hydroxyoctanoate)/bacterial cellulose composites. Advanced Engineering Materials. 14 (6), pp. B330-B343.
Poly(3-hydroxybutyrate) production by Bacillus cereus SPV using sugarcane molasses as the main carbon source (2012)
Akaraonye, E., Moreno, C., Knowles, J.C., Keshavarz, T. and Roy, I. 2012. Poly(3-hydroxybutyrate) production by Bacillus cereus SPV using sugarcane molasses as the main carbon source. Biotechnology Journal. 7 (2), pp. 293-303.

2011

The homopolymer poly(3-hydroxyoctanoate) as a matrix material for soft tissue engineering (2011)
Rai, R., Boccaccini, A.R., Knowles, J.C., Mordon, N., Salih, V., Locke, I.C., Moshrefi-Torbati, M., Keshavarz, T. and Roy, I. 2011. The homopolymer poly(3-hydroxyoctanoate) as a matrix material for soft tissue engineering. Journal of Applied Polymer Science. 122 (6), pp. 3606-3617.
Controlled delivery of gentamicin using poly(3-hydroxybutyrate) microspheres (2011)
Francis, L., Meng, D., Knowles, J.C., Keshavarz, T., Boccaccini, A.R. and Roy, I. 2011. Controlled delivery of gentamicin using poly(3-hydroxybutyrate) microspheres. International Journal of Molecular Sciences. 12 (7), pp. 4294-4314.
Poly-3-hydroxyoctanoate P(3HO), a medium chain length polyhydroxyalkanoate homopolymer from Pseudomonas mendocina (2011)
Rai, R., Yunos, D.M., Boccaccini, A.R., Knowles, J.C., Barker, I.A., Howdle, S.M., Tredwell, G.D., Keshavarz, T. and Roy, I. 2011. Poly-3-hydroxyoctanoate P(3HO), a medium chain length polyhydroxyalkanoate homopolymer from Pseudomonas mendocina. Biomacromolecules. 12 (6), pp. 2126-2136.
Enhanced intracellular Ca(2+) concentrations in Escherichia coli and Bacillus subtilis after addition of oligosaccharide elicitors (2011)
Murphy, T., Nilsson, A., Roy, I., Harrop, A., Dixon, K. and Keshavarz, T. 2011. Enhanced intracellular Ca(2+) concentrations in Escherichia coli and Bacillus subtilis after addition of oligosaccharide elicitors. Biotechnology Letters. 33 (5), pp. 985-991.
Medium chain length polyhydroxyalkanoates, promising new biomedical materials for the future (2011)
Rai, R., Keshavarz, T., Roether, J.A., Boccaccini, A.R. and Roy, I. 2011. Medium chain length polyhydroxyalkanoates, promising new biomedical materials for the future. Materials Science and Engineering R: Reports. 72 (3), pp. 29-47.
Imaging internal features of whole, unfixed bacteria (2011)
Thomson, N., Channon, K., Mokhtar, N.A., Staniewicz, L., Rai, R., Roy, I., Sato, S., Tsuge, T., Donald, A.M., Summers, D. and Sivaniah, E. 2011. Imaging internal features of whole, unfixed bacteria. Scanning. 33 (2), pp. 59-68.
Using electrophoretic deposition to identify protein charge in biological medium (2011)
Meng, D., Francis, L., Roy, I. and Boccaccini, A.R. 2011. Using electrophoretic deposition to identify protein charge in biological medium. Journal of Applied Electrochemistry. 41 (8), pp. 919-923.

2010

Impact of linoleic acid supplementation on lovastatin production in Aspergillus terreus cultures (2010)
Sorrentino, F., Roy, I. and Keshavarz, T. 2010. Impact of linoleic acid supplementation on lovastatin production in Aspergillus terreus cultures. Applied Microbiology and Biotechnology. 88 (1), pp. 65-73.
Multi-functional P(3HB) microsphere/45S5 Bioglass((R))-based composite scaffolds for bone tissue engineering (2010)
Francis, L., Meng, D., Knowles, J.C., Roy, I. and Boccaccini, A.R. 2010. Multi-functional P(3HB) microsphere/45S5 Bioglass((R))-based composite scaffolds for bone tissue engineering. Acta Biomaterialia. 6 (7), pp. 2773-2786.
The influence of tetracycline loading on the surface morphology and biocompatibility of films made from P(3HB) microspheres (2010)
Francis, L., Meng, D., Locke, I.C., Mordon, N., Salih, V., Knowles, J.C., Boccaccini, A.R. and Roy, I. 2010. The influence of tetracycline loading on the surface morphology and biocompatibility of films made from P(3HB) microspheres. Advanced Engineering Materials. 12 (7), pp. B260-B268.
In vitro production of polyhydroxyalkanoates: achievements and applications (2010)
Thomson, N., Roy, I., Summers, D. and Sivaniah, E. 2010. In vitro production of polyhydroxyalkanoates: achievements and applications. Journal of Chemical Technology and Biotechnology. 85 (6), pp. 760-767.
Polyhydroxyalkanoates: bioplastics with a green agenda (2010)
Keshavarz, T. and Roy, I. 2010. Polyhydroxyalkanoates: bioplastics with a green agenda. Current Opinion in Microbiology. 13 (3), pp. 321-326.
Production of polyhydroxyalkanoates: the future green materials of choice (2010)
Akaraonye, E., Keshavarz, T. and Roy, I. 2010. Production of polyhydroxyalkanoates: the future green materials of choice. Journal of Chemical Technology and Biotechnology. 85 (6), pp. 732-743.
Poly(3-hydroxybutyrate) multifunctional composite scaffolds for tissue engineering applications (2010)
Misra, S.K., Ansari, T.I., Valappil, S.P., Mohn, D., Philip, S.E., Stark, W.J., Roy, I., Knowles, J.C., Salih, V. and Boccaccini, A.R. 2010. Poly(3-hydroxybutyrate) multifunctional composite scaffolds for tissue engineering applications. Biomaterials. 31 (10), pp. 2806-2815.
Characterization of carbon nanotube (MWCNT) containing P(3HB)/bioactive glass composites for tissue engineering applications (2010)
Misra, S.K., Ohashi, F., Valappil, S.P., Knowles, J.C., Roy, I., Ravi, S., Silva, P., Salih, V. and Boccaccini, A.R. 2010. Characterization of carbon nanotube (MWCNT) containing P(3HB)/bioactive glass composites for tissue engineering applications. Acta Biomaterialia. 6 (3), pp. 735-742.
Effect of nanoparticulate bioactive glass particles on bioactivity and cytocompatibility of poly(3-hydroxybutyrate) composites (2010)
Misra, S.K., Ansari, T.I., Mohn, D., Valappil, S.P., Brunner, T.J., Stark, W.J., Roy, I., Knowles, J.C., Sibbons, P.D., Valsami-Jones, E., Boccaccini, A.R. and Salih, V. 2010. Effect of nanoparticulate bioactive glass particles on bioactivity and cytocompatibility of poly(3-hydroxybutyrate) composites. Journal of the Royal Society Interface. 7 (44), pp. 453-465.

2009

Electrospun nanofibrous biodegradable polyester coatings on Bioglass®-based glass-ceramics for tissue engineering (2009)
Bretcanu, O., Misra, S.K., Yunos, D.M., Boccaccini, A.R., Roy, I., Kowalczyk, T., Blonski, S. and Kowalewski, T.A. 2009. Electrospun nanofibrous biodegradable polyester coatings on Bioglass®-based glass-ceramics for tissue engineering. Materials Chemistry and Physics. 118 (2-3), pp. 420-426.
Quantitative PCR study on the mode of action of oligosaccharide elicitors on penicillin G production by Penicillium chrysogenum (2009)
Nair, R.R., Roy, I., Bucke, C. and Keshavarz, T. 2009. Quantitative PCR study on the mode of action of oligosaccharide elicitors on penicillin G production by Penicillium chrysogenum. Journal of Applied Microbiology. 107 (4), pp. 1131-1139.
Effect of impeller speed and pH on the production of Poly(3-hydroxybutyrate) using Bacillus cereus SPV (2009)
Philip, S.E., Sengupta, S., Keshavarz, T. and Roy, I. 2009. Effect of impeller speed and pH on the production of Poly(3-hydroxybutyrate) using Bacillus cereus SPV. Biomacromolecules. 10 (4), pp. 691-699.
Incorporation of vitamin E in poly(3hydroxybutyrate)/Bioglass composite films: effect on surface properties and cell attachment (2009)
Misra, S.K., Philip, S.E., Chrzanowski, W., Nazhat, S.N., Roy, I., Knowles, J.C., Salih, V. and Boccaccini, A.R. 2009. Incorporation of vitamin E in poly(3hydroxybutyrate)/Bioglass composite films: effect on surface properties and cell attachment. Journal of the Royal Society Interface. 6 (33), pp. 401-409.
In vitro biocompatibility of 45S5 Bioglass®-derived glass-ceramic scaffolds coated with poly(3-hydroxybutyrate) (2009)
Bretcanu, O., Misra, S.K., Roy, I., Renghini, C., Fiori, F., Boccaccini, A.R. and Salih, V. 2009. In vitro biocompatibility of 45S5 Bioglass®-derived glass-ceramic scaffolds coated with poly(3-hydroxybutyrate). Journal of Tissue Engineering and Regenerative Medicine. 3 (2), pp. 139-148.

2008

Elicitation effects of oligosaccharides on the transcriptional level of bacitracin ABC transporter genes in Bacillus licheniformis (2008)
Murphy, T., Roy, I., Harrop, A., Dixon, K. and Keshavarz, T. 2008. Elicitation effects of oligosaccharides on the transcriptional level of bacitracin ABC transporter genes in Bacillus licheniformis. Biotechnology Letters. 30 (9), pp. 1665-1670.
Polyhydroxyalkanoate biosynthesis in Bacillus cereus SPV under varied limiting conditions and an insight into the biosynthetic genes involved (2008)
Valappil, S.P., Rai, R., Bucke, C. and Roy, I. 2008. Polyhydroxyalkanoate biosynthesis in Bacillus cereus SPV under varied limiting conditions and an insight into the biosynthetic genes involved. Journal of Applied Microbiology. 104 (6), pp. 1624-1635.
Comparison of nanoscale and microscale bioactive glass on the properties of P(3HB)/Bioglass® composites (2008)
Misra, S.K., Mohn, D., Brunner, T.J., Stark, W.J., Philip, S.E., Roy, I., Salih, V., Knowles, J.C. and Boccaccini, A.R. 2008. Comparison of nanoscale and microscale bioactive glass on the properties of P(3HB)/Bioglass® composites. Biomaterials. 29 (12), pp. 1750-1761.
Comparison of nanoscale and microscale bioactive glass on the properties of P(3HB)/Bioglass composites (2008)
Misra, S.K., Mohn, D., Brunner, T.J., Stark, W.J., Philip, S.E., Roy, I., Salih, V., Knowles, J.C. and Boccaccini, A.R. 2008. Comparison of nanoscale and microscale bioactive glass on the properties of P(3HB)/Bioglass composites. Biomaterials. 29 (12), pp. 1750-1761.
Metabolite profiles of interacting mycelial fronts differ for pairings of the wood decay basidiomycete fungus, Stereum hirsutum with its competitors Coprinus micaceus and Coprinus disseminatus (2008)
Peiris, D., Dunn, W.B., Brown, M., Kell, D.B., Roy, I. and Hedger, J.N. 2008. Metabolite profiles of interacting mycelial fronts differ for pairings of the wood decay basidiomycete fungus, Stereum hirsutum with its competitors Coprinus micaceus and Coprinus disseminatus. Metabolomics. 4 (1), pp. 52-62.
Optimisation of β-glucuronidase production from a newly isolated Ganoderma applanatum (2008)
Chouiter, R., Roy, I. and Bucke, C. 2008. Optimisation of β-glucuronidase production from a newly isolated Ganoderma applanatum. Journal of Molecular Catalysis B: Enzymatic. 50 (2-4), pp. 114-120.

2007

Large-scale production and efficient recovery of PHB with desirable material properties, from the newly characterised Bacillus cereus SPV (2007)
Valappil, S.P., Misra, S.K., Boccaccini, A.R., Keshavarz, T., Bucke, C. and Roy, I. 2007. Large-scale production and efficient recovery of PHB with desirable material properties, from the newly characterised Bacillus cereus SPV. Journal of Biotechnology. 132 (3), pp. 251-258.
Biodegradable polymer coated 45S5 Bioglassderived glass-ceramic scaffolds for bone tissue engineering (2007)
Bretcanu, O., Chen, Q., Misra, S.K., Boccaccini, A.R., Roy, I., Verne, E. and Brovarone, C.V. 2007. Biodegradable polymer coated 45S5 Bioglassderived glass-ceramic scaffolds for bone tissue engineering. European Journal of Glass Science and Technology Part A. 48 (5), pp. 227-234.
Effect of oligosaccharide elicitors on bacitracin A production and evidence of transcriptional level control (2007)
Keshavarz, T., Murphy, T., Roy, I., Harrop, A. and Dixon, K. 2007. Effect of oligosaccharide elicitors on bacitracin A production and evidence of transcriptional level control. Journal of Biotechnology. 131 (4), pp. 397-403.
Fabrication and characterization of biodegradable poly(3-hydroxybutyrate) composite containing Bioglass (2007)
Misra, S.K., Nazhat, S.N., Valappil, S.P., Moshrefi-Torbati, M., Wood, R.J.K., Roy, I. and Boccaccini, A.R. 2007. Fabrication and characterization of biodegradable poly(3-hydroxybutyrate) composite containing Bioglass. Biomacromolecules. 8 (7), pp. 2112-2119.
Novel application of oligosaccharides as elicitors for the enhancement of bacitracin A production in cultures of Bacillus licheniformis (2007)
Murphy, T., Parra, R., Radman, R., Roy, I., Harrop, A., Dixon, K. and Keshavarz, T. 2007. Novel application of oligosaccharides as elicitors for the enhancement of bacitracin A production in cultures of Bacillus licheniformis. Enzyme and Microbial Technology. 40 (6), pp. 1518-1523.
Polyhydroxyalkanoates: biodegradable polymers with a range of applications (2007)
Philip, S.E., Keshavarz, T. and Roy, I. 2007. Polyhydroxyalkanoates: biodegradable polymers with a range of applications. Journal of Chemical Technology and Biotechnology. 82 (3), pp. 233-247.
Polyhydroxyalkanoates: biodegradable polymers with a range of applications (2007)
Philip, S.E., Keshavarz, T. and Roy, I. 2007. Polyhydroxyalkanoates: biodegradable polymers with a range of applications. Journal of Chemical Technology and Biotechnology. 82 (3), pp. 233-247.
Poly(3- hydroxybutyrate)/Bioglass® composite films containing carbon nanotubes (2007)
Misra, S.K., Watts, P.C.P., Valappil, S.P., Silva, S.R.P., Boccaccini, A.R. and Roy, I. 2007. Poly(3- hydroxybutyrate)/Bioglass® composite films containing carbon nanotubes. Nanotechnology. 18 (7), p. 075701.
Polyhydroxyalkanoate (PHA) biosynthesis from structurally unrelated carbon sources by a newly characterized Bacillus spp (2007)
Valappil, S.P., Peiris, D., Langley, G.J., Herniman, J.M., Boccaccini, A.R., Bucke, C. and Roy, I. 2007. Polyhydroxyalkanoate (PHA) biosynthesis from structurally unrelated carbon sources by a newly characterized Bacillus spp. Journal of Biotechnology. 127 (3), pp. 475-487.
Polyhydroxyalkanoates in Gram-positive bacteria: insights from the genera Bacillus and Streptomyces (2007)
Valappil, S.P., Boccaccini, A.R., Bucke, C. and Roy, I. 2007. Polyhydroxyalkanoates in Gram-positive bacteria: insights from the genera Bacillus and Streptomyces. Antonie van Leeuwenhoek. 91 (1), pp. 1-17.

2006

Biomedical applications of polyhydroxyalkanoates: an overview of animal testing and in vivo responses (2006)
Valappil, S.P., Misra, S.K., Boccaccini, A.R. and Roy, I. 2006. Biomedical applications of polyhydroxyalkanoates: an overview of animal testing and in vivo responses. Expert Review of Medical Devices. 3 (6), pp. 853-868.
Polyhydroxyalkanoate (PHA)/inorganic phase composites for tissue engineering applications (2006)
Misra, S.K., Valappil, S.P., Roy, I. and Boccaccini, A.R. 2006. Polyhydroxyalkanoate (PHA)/inorganic phase composites for tissue engineering applications. Biomacromolecules. 7 (8), pp. 2250-2257.

2004

Biosynthesis of polyhydroxyalkanoic acids by Streptomyces coelicolor (2004)
Valappil, S.P., Bhatia, Y., Bucke, C. and Roy, I. 2004. Biosynthesis of polyhydroxyalkanoic acids by Streptomyces coelicolor. e-Polymers.

2003

5-Aminolevulinic acid synthase: mechanism, mutations and medicine (2003)
Shoolingin-Jordan, P., Al-Daihan, S., Alexeev, D., Baxter, R.L., Bottomley, S.S., Kahari, I.D., Roy, I., Sarwar, M., Sawyer, L. and Wang, S.F. 2003. 5-Aminolevulinic acid synthase: mechanism, mutations and medicine. Biochimica et Biophysica Acta: Proteins and Proteomics. 1647 (1-2), pp. 361-365.
5-aminolevulinic acid synthase: mechanism, mutations and medicine (2003)
Shoolingin-Jordan, P., Al-Daihan, S., Alexeev, D., Baxter, R.L., Bottomley, S.S., Kahari, D., Roy, I., Sarwar, M., Sawyer, L. and Wang, S.F. 2003. 5-aminolevulinic acid synthase: mechanism, mutations and medicine. Biochimica et Biophysica Acta: Proteins and Proteomics. 1647 (1-2), pp. 361-366.

2002

A possible role of poly-3-hydroxybutyric acid in antibiotic production in Streptomyces (2002)
Verma, S., Bhatia, Y., Valappil, S.P. and Roy, I. 2002. A possible role of poly-3-hydroxybutyric acid in antibiotic production in Streptomyces. Archives of Microbiology. 179 (1), pp. 66-69.

1998

Phosphorylation of the periplasmic binding protein in two transport systems for arginine incorporation in Escherichia coli K-12 is unrelated to the function of the transport system (1998)
Celis, R.T.F., Leadlay, P.F., Roy, I. and Hansen, A. 1998. Phosphorylation of the periplasmic binding protein in two transport systems for arginine incorporation in Escherichia coli K-12 is unrelated to the function of the transport system. Journal of Bacteriology. 180 (18), pp. 4828-4833.

1996

The masked cysteine residues in methylmalonyl-CoA mutase from Propionibacterium shermanii are essential for catalytic activity (1996)
Roy, I. 1996. The masked cysteine residues in methylmalonyl-CoA mutase from Propionibacterium shermanii are essential for catalytic activity. FEBS Letters. 394 (2), pp. 126-128.

1992

Physical map location of the new Escherichia coli gene sbm (1992)
Roy, I. and Leadlay, P.F. 1992. Physical map location of the new Escherichia coli gene sbm. Journal of Bacteriology. 174 (17), pp. 5763-5764.

2016

Biomedical applications of polyhydroxyalkanoates (2016)
Roy, I., Lizarraga Valderrama, L., Panchal, B. and Boccaccini, A. 2016. Biomedical applications of polyhydroxyalkanoates. in: Reis, R.L. and Neves, N. (ed.) Biomaterials from nature for advanced devices and therapies Oxford Wiley.

2015

Production, chemistry and properties of biopolymers in food science (2015)
Puthussery, H., Prasad, R., Gorazda, K. and Roy, I. 2015. Production, chemistry and properties of biopolymers in food science. in: Cirillo, G., Spizzirri, U. and Iemma, F. (ed.) Functional polymers in food science: from technology to biology: volume 1 food packaging London Wiley.
Novel cardiac patch development using biopolymers and biocomposites (2015)
Dubey, P., Boccaccini, A. and Roy, I. 2015. Novel cardiac patch development using biopolymers and biocomposites. in: Yang, Y. and Xu, H. (ed.) Lightweight materials from biopolymers and biofibers Washington DC, USA American Chemical Society.

2013

Polyhydroxyalkanoates: the natural polymers produced by bacterial fermentation (2013)
Panchal, B., Bagdadi, A. and Roy, I. 2013. Polyhydroxyalkanoates: the natural polymers produced by bacterial fermentation. in: Advances in natural polymer Elsevier.

2011

Polyhydroxyalkanoates: the emerging new green polymers of choice (2011)
Rai, R. and Roy, I. 2011. Polyhydroxyalkanoates: the emerging new green polymers of choice. in: Sharma, S.K. and Mudhoo, A. (ed.) A handbook of applied biopolymer technology: synthesis, degradation and applications Royal Society of Chemistry.

2010

Polyhydroxyalkanoates, the emerging new green polymers of choice (2010)
Rai, R. and Roy, I. 2010. Polyhydroxyalkanoates, the emerging new green polymers of choice. in: Biodegradable polymers and green chemistry Royal Society of Chemistry. pp. 79-97
Microbial production of biodegradable polymers and their role in cardiac stent development (2010)
Basnett, P. and Roy, I. 2010. Microbial production of biodegradable polymers and their role in cardiac stent development. in: Mendez-Vilas, A. (ed.) Current research, technology and education topics in applied microbiology and microbial biotechnology Formatex Research Center.
Biodegradable polymers and their role in coronary stent development (2010)
Basnett, P. and Roy, I. 2010. Biodegradable polymers and their role in coronary stent development. in: Current research in technology and education topics in applied microbiology and microbial biotechnology Formatex Research Center.

2009

Microbial PHA biosynthesis and its biomedical applications (2009)
Roy, I., Philip, S.E., Francis, L., Rai, R., Keshavarz, T., Misra, S.K., Decheng, M. and Boccaccini, A.R. 2009. Microbial PHA biosynthesis and its biomedical applications. in: Proceedings of Euromat 2009, Glasgow, 7 - 10 September 2009 Euromat.
A class IV PHA synthase from Bacillus cereus SPV (2009)
Philip, S.E. and Roy, I. 2009. A class IV PHA synthase from Bacillus cereus SPV. in: Kiekens, P., Nierstrasz, V. and Lenting, H.B.M. (ed.) Proceedings of the international conference on textile and polymer biotechnology 6th Het Pand, Ghent, Belgium 23-25 September 2009 Ghent University. Department of Textiles Ghent.
P(3HB) production by Bacillus cereus SPV using sucrose as a carbon source (2009)
Akaraonye, E., Keshavarz, T. and Roy, I. 2009. P(3HB) production by Bacillus cereus SPV using sucrose as a carbon source. in: Kiekens, P., Nierstrasz, V. and Lenting, H.B.M. (ed.) Proceedings of the international conference on textile and polymer biotechnology 6th Het Pand, Ghent, Belgium 23-25 September 2009 Ghent University. Department of Textiles Ghent.

2008

Polyhydroxyalkanoates: a new generation of biotechnologically produced biodegradable polymers (2008)
Roy, I. and Philip, S.E. 2008. Polyhydroxyalkanoates: a new generation of biotechnologically produced biodegradable polymers. in: Richter, F.W. (ed.) Biotechnology: research, technology and applications New York Nova Science Publishers. pp. 1-48
Fabrication of a novel (2008)
Roy, I. and Philip, S.E. 2008. Fabrication of a novel. in: Richter, F.W. (ed.) Biotechnology: research, technology and applications New York Nova Science Publishers. pp. 1-48
Optimisation studies of multiple elicitor addition in microbial systems: P.Chrysogenum and B.Lichiniformis (2008)
Nair, R.R., Murphy, T., Roy, I., Harrop, A., Dixon, K. and Keshavarz, T. 2008. Optimisation studies of multiple elicitor addition in microbial systems: P.Chrysogenum and B.Lichiniformis. in: Marino, G., Bardone, E. and Viglia, A. (ed.) IBIC2008 - 1st International Conference on Industrial Biotechnology AIDIC Servizi S.r.l..

2005

Towards unravelling the elicitation mechanism in cultures of Penicillium chrysogenin: Chrysogenin elicitation (2005)
Nair, R.R., Radman, R., Roy, I., Bucke, C. and Keshavarz, T. 2005. Towards unravelling the elicitation mechanism in cultures of Penicillium chrysogenin: Chrysogenin elicitation. in: Pierucci, S. (ed.) 7th Italian Conference on Chemical and Process Engineering: ICheaP 7, May 15-16, 2005, Giardini Di Naxos, Italy Italy Associazione Italiana Di Ingegneria Chimica.

1997

A Methylmalonyl-CoA mutase in Escherichia coli? (1997)
Roy, I. and Leadlay, P.F. 1997. A Methylmalonyl-CoA mutase in Escherichia coli? in: Ahmad, F. (ed.) Advances in gene technology: biomolecular design, form and function Nature Publishing Group.

2014

Poly(3-hydroxyoctanoate): a novel natural material for cardiac tissue engineering (2014)
Dubey, P., Bagdadi, A., Boccaccini, A., Knowles, J., Stevens, M., Harding, S., Roy, I. and Ravi, S. 2014. Poly(3-hydroxyoctanoate): a novel natural material for cardiac tissue engineering. BHF Regenerative Medicine Centre Joint Annual and SAB meetings. Imperial College, London 31 Jul 2014
Nerve tissue engineering using blends of polyhydroxyalkanoates (2014)
Lizarraga Valderrama, L., Percy, L. and Roy, I. 2014. Nerve tissue engineering using blends of polyhydroxyalkanoates. 8th International Conference on Polymer and Fiber Biotechnology. Braga, Portugal 25 May 2014
Production of polyhydroxyalkanoates and their medical applications (2014)
Roy, I. 2014. Production of polyhydroxyalkanoates and their medical applications. International Symposium on Biopolymers. Santos, Brazil 30 Sep 2014

2012

Enhanced production of the polyhydroxyalkanoate, P(3HB), from cacillus cereus SPV and its applications in cartilage regeneration (2012)
Everest, A., Keshavarz, T. and Roy, I. 2012. Enhanced production of the polyhydroxyalkanoate, P(3HB), from cacillus cereus SPV and its applications in cartilage regeneration. Gordon Research Conference on Biopolymers. Salve Regina University, Newport, Rhode Island, USA 3-8 June 2012

2011

Polyhydroxyalkanoate (PHA): bacterial cellulose composites for biomedical applications (2011)
Basnett, P., Smith, C.L., Boccaccini, A.R., Knowles, J.C., Keshavarz, T. and Roy, I. 2011. Polyhydroxyalkanoate (PHA): bacterial cellulose composites for biomedical applications. European Society of Biomaterials. Dublin, Ireland Sept 2011
Production of polyhydroxyalkanoates and their medical applications (2011)
Roy, I., Akaraonye, E., Francis, L., Rai, R., Basnett, P. and Keshavarz, T. 2011. Production of polyhydroxyalkanoates and their medical applications. 7th International Conference on Polymer and Textile Biotechnology. Milan, Italy 2nd - 4th March 2011
Production of polyhydroxyalkanoates and their biomedical applications (2011)
Roy, I., Akaraonye, E., Francis, L., Rai, R., Basnett, P. and Keshavarz, T. 2011. Production of polyhydroxyalkanoates and their biomedical applications. Euro BioMat 2011 - European Symposium on Biomaterials and Related Areas. Jena, Germany

2010

Production of SCL and MCL polyhydroxyalkanoates and their applications (2010)
Roy, I., Akaraonye, E., Francis, L., Rai, R. and Boccaccini, A.R. 2010. Production of SCL and MCL polyhydroxyalkanoates and their applications. 12th International Symposium on Biodegradable Polyesters. Stuttgart, Germany.
Multifunctional P(3HB) microsphere/45S Bioglass ®-based composite scaffolds for bone tissue engineering (2010)
Francis, L., Meng, D., Boccaccini, A.R. and Roy, I. 2010. Multifunctional P(3HB) microsphere/45S Bioglass ®-based composite scaffolds for bone tissue engineering. 12th International Symposium on Biodegradable Polyesters. Stuttgart, Germany.
In vitro mutagenesis of the type IV polyhydroxyalkanoate synthase from bacillus cereus SPV (2010)
Basnett, P., Philip, S.E., Markhiv, A., Vydayanathan, A. and Roy, I. 2010. In vitro mutagenesis of the type IV polyhydroxyalkanoate synthase from bacillus cereus SPV. 12th International Symposium on Biodegradable Polyesters. Stuttgart, Germany.
Enhanced and economical production of poly(3-hydroxybutyrate), a biodegradable polymer and its applications (2010)
Akaraonye, E., Safarikova, M., Keshavarz, T. and Roy, I. 2010. Enhanced and economical production of poly(3-hydroxybutyrate), a biodegradable polymer and its applications. 12th International Symposium on Biodegradable Polyesters. Stuttgart, Germany.
Fabrication of a novel poly(3-hydroxyoctanoate) / nanoscale bioactive glass composite film with potential as a multifunctional wound dressing (2010)
Rai, R., Boccaccini, A.R., Knowles, J.C., Locke, I.C., Gordge, M.P., McCormick, A., Salih, V., Mordon, N., Keshavarz, T. and Roy, I. 2010. Fabrication of a novel poly(3-hydroxyoctanoate) / nanoscale bioactive glass composite film with potential as a multifunctional wound dressing. 5th international conference on times of polymers (TOP) and composites. Ischia, Italy 20–23 June 2010

2009

Polyhydroxyalkanoate synthases-enzymes involved in biodegradable polymer synthesis (2009)
Roy, I., Philip, S.E. and Keshavarz, T. 2009. Polyhydroxyalkanoate synthases-enzymes involved in biodegradable polymer synthesis. COST Action 868: Biotechnical Functionalisation of Renewable Polymeric Materials : Meeting on "Biotechnology and Biopolymers in Textile, Packaging, Cosmetics and Medical Applications". Istanbul, Turkey 19 - 20 Feb 2009

2008

Microbial biosynthesis of PHAs and its applications (2008)
Roy, I., Philip, S.E., Francis, L., Rai, R., Valappil, S.P., Markiv, A., Keshavarz, T., Misra, S.K., Decheng, M. and Boccaccini, A.R. 2008. Microbial biosynthesis of PHAs and its applications. COST Action 868: Biotechnical Functionalisation of Renewable Polymeric Materials: 2008 Annual Workshop (combined Working Group and Management Committee meeting). Varna, Bulgaria 18 -19 Sep 2008
Microbial PHA biosynthesis and its applications (2008)
Roy, I., Philip, S.E., Francis, L., Rai, R., Valappil, S.P., Markiv, A., Keshavarz, T., Misra, S.K., Decheng, M. and Boccaccini, A.R. 2008. Microbial PHA biosynthesis and its applications. 11th International Symposium on Biodegradable Polyesters. Massey University in Auckland, New Zealand 23 - 26 Nov 2008
Production of medium chain length polyhydroxyalkanoates using Pseudomonas species (2008)
Rai, R., Keshavarz, T. and Roy, I. 2008. Production of medium chain length polyhydroxyalkanoates using Pseudomonas species. 11th International Symposium on Biodegradable Polyesters. Massey University in Auckland, New Zealand 23 - 26 Nov 2008
Polyhydroxyalkanoate synthase in Bacillus cereus SPV, a class IV PHA synthase (2008)
Philip, S.E., Odell, M., Keshavarz, T. and Roy, I. 2008. Polyhydroxyalkanoate synthase in Bacillus cereus SPV, a class IV PHA synthase. 11th International Symposium on Biodegradable Polyesters. Massey University in Auckland, New Zealand 23 - 26 Nov 2008
Polyhydroxyalkanoate synthasis using Bacillus cereus SPV (2008)
Francis, L., Keshavarz, T. and Roy, I. 2008. Polyhydroxyalkanoate synthasis using Bacillus cereus SPV. COST Action 868: Biotechnical Functionalisation of Renewable Polymeric Materials: 2008 Annual Workshop (combined Working Group and Management Committee meeting). Varna, Bulgaria 18 -19 Sep 2008

2007

PHA biosynthesis in Bacillus cereus SPV and its applications (2007)
Roy, I., Valappil, S.P., Misra, S.K. and Boccaccini, A.R. 2007. PHA biosynthesis in Bacillus cereus SPV and its applications. COST Action 868: Biotechnical Functionalisation of Renewable Polymeric Materials: first annual workshop. Graz, Austria 12 - 14 Sep 2007
PHA Biosynthesis in Bacillus cereus SPV (2007)
Roy, I., Philip, S.E., Rai, R. and Valappil, S.P. 2007. PHA Biosynthesis in Bacillus cereus SPV. International Conference on Biodegradable Polymers: their production, characterisation and application. SCI, London 10 Dec 2007
Production of Polyhydroxyalkanoates from Bacillus cereus SPV under different nutrient limiting conditions (2007)
Rai, R., Padinhara, S.V., Keshavarz, T. and Roy, I. 2007. Production of Polyhydroxyalkanoates from Bacillus cereus SPV under different nutrient limiting conditions. COST Action 868: Biotechnical Functionalisation of Renewable Polymeric Materials: first annual workshop. Graz, Austria 12 - 14 Sep 2007
Production of medium chain length polyhydroxyalkanoates using pseudomonas species UOW0417398 (2007)
Rai, R., Keshavarz, T. and Roy, I. 2007. Production of medium chain length polyhydroxyalkanoates using pseudomonas species UOW0417398. International Conference on Biodegradable Polymers: their production, characterisation and application. SCI, London 10 Dec 2007
Polyhydroxy-alkanoates - the biodegradable polymers (2007)
Philip, S.E., Odell, M., Keshavarz, T. and Roy, I. 2007. Polyhydroxy-alkanoates - the biodegradable polymers. International Conference on Biodegradable Polymers: their production, characterisation and application. SCI, London 10 Dec 2007
Biosynthesis of polyhydroxyalkanoates and their applications (2007)
Francis, L., Keshavarz, T. and Roy, I. 2007. Biosynthesis of polyhydroxyalkanoates and their applications. International Conference on Biodegradable Polymers: their production, characterisation and application. SCI, London 10 Dec 2007

2006

Nanoindentation testing of biodegradabale polymers (2006)
Wood, R.J.K., Dan, S., Moshrefi-Torbati, M., Misra, S.K., Valappil, S.P., Boccaccini, A.R. and Roy, I. 2006. Nanoindentation testing of biodegradabale polymers. Proceedings of CAMTEC Workshop. University of Cambridge, Cambridge, UK 11 Apr 2006
PHA biosynthesis in Bacillus cereus SPV and its applications (2006)
Roy, I., Valappil, S.P., Misra, S.K. and Boccaccini, A.R. 2006. PHA biosynthesis in Bacillus cereus SPV and its applications. Proceedings of the International Symposium on Biological Polyesters. Minneapolis, USA 27 - 31 Aug 2006
Development of polyhydroxyalkanoates/Bioglass® composite tissue scaffolds for tissue engineering applications (2006)
Misra, S.K., Valappil, S.P., Nazhat, S.N., Moshrefi-Torbati, M., Roy, I. and Boccaccini, A.R. 2006. Development of polyhydroxyalkanoates/Bioglass® composite tissue scaffolds for tissue engineering applications. Proceedings of the 20th European Conference on Biomaterials, European Society of Biomaterials. Nantes, FRANCE 27 Sep - 01 Oct 2006
From bacteria to tissue engineering applications-usage of polyhydroxyalkanoates for biomedical applications (2006)
Misra, S.K., Nazhat, S.N., Torbati, M.M., Silva, S.R.P., Roy, I. and Boccaccini, A.R. 2006. From bacteria to tissue engineering applications-usage of polyhydroxyalkanoates for biomedical applications. Proceedings of the International Conference on the Design of Biomaterials. Kanpur, India 08 - 11 Dec 2006

2005

Polyhydroxyalkanoate synthases: the enzymes involved in biodegradable polymer synthesis (2005)
Valappil, S.P., Philip, S.E., Odell, M., Keshavarz, T. and Roy, I. 2005. Polyhydroxyalkanoate synthases: the enzymes involved in biodegradable polymer synthesis. Proceedings of Frontiers in Chemical Biology: Mechanistic Enzymology and Biocatalysis. Exeter, UK 31 Aug - 02 Sep 2005
Large scale production of P(3HB) from newly isolated Bacillus sp. (2005)
Valappil, S.P., Keshavarz, T., Bucke, C. and Roy, I. 2005. Large scale production of P(3HB) from newly isolated Bacillus sp. Proceedings of the 1st International Conference on Environmental Industrial and Applied Microbiology. Badajoz, Spain 15 - 18 Mar 2005
Effect of various carbon sources on the production of PHAs from the newly isolated Bacillus sp. (2005)
Valappil, S.P., Bucke, C. and Roy, I. 2005. Effect of various carbon sources on the production of PHAs from the newly isolated Bacillus sp. Proceedings of the International Union of Microbiological Societies Congress, IUMS. San Fransisco, USA 23 - 28 Jul 2005
Natural biodegradable polymers from the Polyhydroxyalkanoate family emerging as a promising material for biomedical applications (2005)
Misra, S.K., Boccaccini, A.R., Valappil, S.P. and Roy, I. 2005. Natural biodegradable polymers from the Polyhydroxyalkanoate family emerging as a promising material for biomedical applications. Proceedings of 'a Forecast of the Future for Biomaterials' Professor Larry L. Hench Retirement Symposium. London, UK 29 - 30 Sep 2005
The metabolic role of methymalonyl CoA mutase in Escherichia coli (2005)
Kannan, S.M., Dwek, M., Bucke, C. and Roy, I. 2005. The metabolic role of methymalonyl CoA mutase in Escherichia coli. Proceedings of Viteomics: structure and function of vitamins and cofactors. Cambridge, UK 2005
Polysaccharides and polysaccharide-modifying enzymes in Ganoderma species (2005)
Chouiter, R., Roy, I. and Bucke, C. 2005. Polysaccharides and polysaccharide-modifying enzymes in Ganoderma species. Proceedings of the 13th European Carbohydrate Symposium. Bratislava, Slovakia 21 - 26 Aug 2005
Polysaccharide-modifying enzymes from Ganoderma species and their applications (2005)
Chouiter, R., Roy, I. and Bucke, C. 2005. Polysaccharide-modifying enzymes from Ganoderma species and their applications. Proceedings of the 1st International Conference on Environmental Industrial and Applied Microbiology. Badajoz, Spain 15 - 18 Mar 2005
Phylogenetic relationships between Basidiomycetes believed to be Ganoderma species based on distance analysis of their 5.8S, ITS1 and ITS2 rDNA sequences (2005)
Chouiter, R., Roy, I. and Bucke, C. 2005. Phylogenetic relationships between Basidiomycetes believed to be Ganoderma species based on distance analysis of their 5.8S, ITS1 and ITS2 rDNA sequences. Proceedings of the 1st International Conference on Environmental Industrial and Applied Microbiology. Badajoz, Spain 15 - 18 Mar 2005

2004

‘Identification and isolation of polyhydroalkanoates and cloning of PHA biosynthetic genes from Bacillus cereus SPV (2004)
Valappil, S.P., Bucke, C. and Roy, I. 2004. ‘Identification and isolation of polyhydroalkanoates and cloning of PHA biosynthetic genes from Bacillus cereus SPV. Proceedings of the International Symposium on Biological Polyesters, ISBP. Beijing, China 22 - 28 Aug 2004
Polyhydroxyalkanoate production by Bacillus cereus SPV (2004)
Roy, I. 2004. Polyhydroxyalkanoate production by Bacillus cereus SPV. Proceedings of the International Symposium on Biological Polyesters, ISBP. Beijing, China 22 - 28 Aug 2004
Carbohydrates and carbohydrate active enzymes in Ganoderma applanatum (2004)
Budala, S., Bucke, C. and Roy, I. 2004. Carbohydrates and carbohydrate active enzymes in Ganoderma applanatum. Proceedings of the 22nd International Carbohydrate Symposium. Glasgow, UK 23 - 27 Jul 2004

2003

Biosynthesis of medium chain length polyhydroxyalakanoic acids by Streptomyces coelicolor (2003)
Valappil, S.P., Bucke, C. and Roy, I. 2003. Biosynthesis of medium chain length polyhydroxyalakanoic acids by Streptomyces coelicolor. ICBP 2003. Proceedings of the 1st IUPAC International Conference on Bio-Based Polymers. Saitama, Japan 12 - 14 Nov 2003

2002

Biosynthesis of polyhydroxyalkanoates by Streptomyces coelicolor (2002)
Valappil, S.P., Bucke, C. and Roy, I. 2002. Biosynthesis of polyhydroxyalkanoates by Streptomyces coelicolor. Proceedings of the International Symposium on Biological Polyesters. Munster, Germany 22 - 26 Sep 2002

2001

Production of polyhydroxybutyrate by streptomyces (2001)
Verma, S. and Roy, I. 2001. Production of polyhydroxybutyrate by streptomyces. Proceedings of the Gordon Research Conference. Connecticut, USA 2001

1998

Metabolic Engineering, a route to the production of novel products (1998)
Roy, I. 1998. Metabolic Engineering, a route to the production of novel products. Proceedings of the National Conference on Bioprocessing and R-DNA Technology. Central Drug Research Institute, Lucknow, India 27 - 28 Mar 1998

1990

Mechanism and structure of a coenzyme-B12 dependent enzyme (1990)
Roy, I., Patchett, M.L., Keep, N.H. and Leadlay, P.F. 1990. Mechanism and structure of a coenzyme-B12 dependent enzyme. Proceedings of the Royal Society of Chemistry Fifth International Symposium on the Mechanisms of Reactions in Solution. University of Kent, UK 02 - 06 Jul 1990

1989

The expression of adenosylcobalamin dependent methylmalonyl-CoA mutase from Propionibacterium shermanii in Escherichia coli (1989)
McKie, N., Keep, N.H., Roy, I., Patchett, M.L. and Leadlay, P.F. 1989. The expression of adenosylcobalamin dependent methylmalonyl-CoA mutase from Propionibacterium shermanii in Escherichia coli. Proceedings of the Royal Society of Chemistry International Symposium on the Molecular Mechanisms in Bioorganic Processes. University of Newcastle upon Tyne, UK 17 - 20 Jul 1989

2014

Polyhydroxyalkanoate (PHA) based blends, composites and nanocomposites (2014)
Roy, I. and Visakh, P.M. (ed.) 2014. Polyhydroxyalkanoate (PHA) based blends, composites and nanocomposites. London Royal Society of Chemistry.

Browse

Browse our directory to find staff profiles containing contact information, biography and list of publications.

Related links

Research strategy
Our University

Discover how the University of Westminster is organised and who makes the University tick.