Dr Pascale Gerbault

Lecturer

+44 20 7911 5000 ext 64132
115 New Cavendish Street London W1W 6UW

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I joined the Department of Life Sciences at the University of Westminster in September 2016 as a Lecturer in Molecular Biology and Genetics and hold a Honorary Research Associate status in the Department of Genetics, Evolution and Environment at University College London.

I am an evolutionary biologist, experienced in analyzing genetic data using simulation modeling approaches to infer evolutionary processes shaping patterns of genetic diversity. I aim to apply my skills to investigate the evolution and spread of infectious diseases.

I studied for degree in Life Sciences and Anthropology in France, Molecular Biology in Canada, and learned how to apply programming skills to test evolutionary hypotheses in Switzerland. 

PhD

2013
Modelling demographic and evolutionary history: Integrating genetic and archaeological data.

 - Course to PhD students: Introduction to simulation modeling in archaeology and population genetics in R (UCL, 2015); Course on introduction to statistics using R (PhDs and postdoctoral researchers, University of Bristol, 2014); Course on ‘Introduction to programming in Python’ (UCL - LeCHE, 2010)

- Course to M.Sc. students: Seminar series Introduction to Population Genetics and Human Evolution (Anthropological and Archaeological Genetics module, UCL, 2010-2015); Teaching Assistant in Biomathematics (University of Geneva, Switzerland, 2008)

My PhD, based in University College London with Prof. Mark Thomas, was part of a European FP7 framework (LeCHE) and focused on using modeling approaches to investigate evolutionary hypotheses while integrating archaeology, anthropology and genetics data, more specifically looking at the evolution of lactase persistence in Europe, the distribution of the EDAR variant in Asia, and mitochondrial DNA diversity in domestic goats.

I was then involved in a Leverhulme Trust funded project “Hunter-Gatherer Resilience” led by Anthropologist Dr Andrea Migliano, to investigate genetic adaptations in short-stature hunter-gatherer (Pygmy) populations from the Congo and the Philippines.

I have also contributed to archaeological research with collaborators in the School of Chemistry, University of Bristol, and in the Museum national d'Histoire Naturelle in Paris. I thrive in diverse and interdisciplinary research.

2017

Investigating mitochondrial DNA relationships in Neolithic Western Europe through serial coalescent simulations (2017)
Rivollat, M., Rottier, S., Couture, C., Pemonge, M.H., Mendisco, F., Thomas, M.G., Deguilloux, M.F. and Gerbault, P. 2017. Investigating mitochondrial DNA relationships in Neolithic Western Europe through serial coalescent simulations. European Journal of Human Genetics. 25, pp. 388-392.

2016

A genomic history of Aboriginal Australia (2016)
Malaspinas, A.S., Westaway, M.C., Muller, C., Sousa, V.C., Lao, O., Alves, I., Bergström, A., Athanasiadis, G., Cheng, J.Y., Crawford, J.E., Heupink, T.H., Macholdt, E., Peischl, S., Rasmussen, S., Schiffels, S., Subramanian, S., Wright, J.L., Albrechtsen, A., Barbieri, C., Dupanloup, I., Eriksson, A., Margaryan, A., Moltke, I., Pugach, I., Korneliussen, T.S., Levkivskyi, I.P., Moreno-Mayar, J.V., Ni, S., Racimo, F., Xue, Y., Sikora, M., Aghakhanian, F.A., Brucato, N., Brunak, S., Campos, P.F., Clark, W., Ellingvåg, S., Fourmile, G., Gerbault, P., Injie, D., Koki, G., Leavesley, M., Logan, B., Lynch, A., Matisoo-Smith, E.A., McAllister, P.J., Mentzer, A.J., Metspalu, M., Migliano, A.B., Murgha, L., Phipps, M.E., Pomat, W., Reynolds, D., Ricaut, F.X., Siba, P., Thomas, M.G., Wales, T., Wall, C.M., Oppenheimer, S.J., Tyler-Smith, C., Durbin, R., Dortch, J., Manica, A., Schierup, M.H., Foley, R.A., Lahr, M.M., Bowern, C., Wall, J.D., Mailund, T., Stoneking, M., Nielsen, R., Sandhu, M.S., Excoffier, L., Lambert, D.M. and Willerslev, E. 2016. A genomic history of Aboriginal Australia. Nature. 538
, pp. 207-214.
Statistically robust representation and comparison of mortality profiles in archaeozoology (2016)
Gerbault, P., Gillis, R., Vigne, J.D., Tresset, A., Bréhard, S. and Thomas, M.G. 2016. Statistically robust representation and comparison of mortality profiles in archaeozoology. Journal of Archaeological Science. 71, pp. 24-32.
Competition for Cooperation: variability, benefits and heritability of relational wealth in hunter-gatherers (2016)
Chaudhary, N., Salali, G.D., Thompson, J., Rey, A., Gerbault, P., Stevenson, E.G., Dyble, M., Smith, D., Mace, R., Vinicius, L. and Migliano, A.B. 2016. Competition for Cooperation: variability, benefits and heritability of relational wealth in hunter-gatherers. Scientific Reports. 6, p. 29120.
Introductory Editorial: Evolutionary Genomics (2016)
Itan, Y., Pines, G. and Gerbault, P. 2016. Introductory Editorial: Evolutionary Genomics. Evolutionary Bioinformatics. 11 (Suppl 2), pp. 53-55.

2015

Forward-in-Time, Spatially Explicit Modeling Software to Simulate Genetic Lineages Under Selection (2015)
Currat, M., Gerbault, P., Di, D., Nunes, J.M. and Sanchez-Mazas, A. 2015. Forward-in-Time, Spatially Explicit Modeling Software to Simulate Genetic Lineages Under Selection. Evolutionary Bioinformatics. 11 (Supp-2), pp. 27-39.
Greenlandic Inuit show genetic signatures of diet and climate adaptation (2015)
Fumagalli, M., Moltke, I., Grarup, N., Racimo, F., Bjerregaard, P., Jørgensen, M.E., Korneliussen, T.S., Gerbault, P., Skotte, L., Linneberg, A., Christensen, C., Brandslund, I., Jørgensen, T., Huerta-Sánchez, E., Schmidt, E.B., Pedersen, O., Hansen, T., Albrechtsen, A. and Nielsen, R. 2015. Greenlandic Inuit show genetic signatures of diet and climate adaptation. Science. 349
, pp. 1343-1347.
Widespread exploitation of the honeybee by early Neolithic farmers (2015)
Roffet-Salque, M., Regert, M., Evershed, R.P., Outram, A.K., Cramp, L.J., Decavallas, O., Dunne, J., Gerbault, P., Mileto, S., Mirabaud, S., Paakkonen, M., Smyth, J., Soberl, L., Whelton, H.L., Alday-Ruiz, A., Asplund, H., Bartkowiak, M., Bayer-Niemeier, E., Belhouchet, L., Bernardini, F., Budja, M., Cooney, G., Cubas, M., Danaher, E.M., Diniz, M., Domboroczki, L., Fabbri, C., Gonzalez-Urquijo, J.E., Guilaine, J., Hachi, S., Hartwell, B.N., Hofmann, D., Hohle, I., Ibanez, J.J., Karul, N., Kherbouche, F., Kiely, J., Kotsakis, K., Lueth, F., Mallory, J.P., Manen, C., Marciniak, A., Maurice-Chabard, B., Mc Gonigle, M.A., Mulazzani, S., Ozdogan, M., Peric, O.S., Peric, S.R., Petrasch, J., Petrequin, A.M., Petrequin, P., Poensgen, U., Pollard, C.J., Poplin, F., Radi, G., Stadler, P., Stauble, H., Tasic, N., Urem-Kotsou, D., Vukovic, J.B., Walsh, F., Whittle, A., Wolfram, S., Zapata-Pena, L. and Zoughlami, J. 2015. Widespread exploitation of the honeybee by early Neolithic farmers. Nature. 527
, pp. 226-230.

2014

Storytelling and story testing in domestication (2014)
Gerbault, P., Allaby, R.G., Boivin, N., Rudzinski, A., Grimaldi, I.M., Pires, J.C., Climer Vigueira, C., Dobney, K., Gremillion, K.J., Barton, L., Arroyo-Kalin, M., Purugganan, M.D., Rubio de Casas, R., Bollongino, R., Burger, J., Fuller, D.Q., Bradley, D.G., Balding, D.J., Richerson, P.J., Gilbert, M.T., Larson, G. and Thomas, M.G. 2014. Storytelling and story testing in domestication. Proceedings of the National Academy of Sciences of the United States of America. 111 (17), pp. 6159-6164.

2013

The onset of lactase persistence in Europe (2013)
Gerbault, P. 2013. The onset of lactase persistence in Europe. Human Heredity. 76 (3-4), pp. 154-161.
How long have adult humans been consuming milk? (2013)
Gerbault, P., Roffet-Salque, M., Evershed, R.P. and Thomas, M.G. 2013. How long have adult humans been consuming milk? IUBMB Life. 65 (12), pp. 983-990.
Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant (2013)
Kamberov, Y.G., Wang, S., Tan, J., Gerbault, P., Wark, A., Tan, L., Yang, Y., Li, S., Tang, K., Chen, H., Powell, A., Itan, Y., Fuller, D., Lohmueller, J., Mao, J., Schachar, A., Paymer, M., Hostetter, E., Byrne, E., Burnett, M., McMahon, A.P., Thomas, M.G., Lieberman, D.E., Jin, L., Tabin, C.J., Morgan, B.A. and Sabeti, P.C. 2013. Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant. Cell. 152 (4), pp. 691-702.

2012

Evaluating demographic models for goat domestication using mtDNA sequences (2012)
Gerbault, P., Powell, A. and Thomas, M.G. 2012. Evaluating demographic models for goat domestication using mtDNA sequences. Anthropozoologica. 47 (2), pp. 64-76.
The evolution of lactase persistence in Europe. A synthesis of archaeological and genetic evidence (2012)
Leonardi, M, Gerbault, P., Thomas, M.G. and Burger, J. 2012. The evolution of lactase persistence in Europe. A synthesis of archaeological and genetic evidence. International Dairy Journal. 22 (2), pp. 88-97.

2011

mtDNA and Y‐chromosome diversity in Aymaras and Quechuas from Bolivia: Different stories and special genetic traits of the Andean Altiplano populations (2011)
Gayà‐Vidal, M., Moral, P., Saenz‐Ruales, N., Gerbault, P., Tonasso, L., Villena, M., Vasquez, R., Bravi, C.M. and Dugoujon, J.M. 2011. mtDNA and Y‐chromosome diversity in Aymaras and Quechuas from Bolivia: Different stories and special genetic traits of the Andean Altiplano populations. American Journal of Physical Anthropology. 145 (2), pp. 215-230.
Evolution of lactase persistence: an example of human niche construction (2011)
Gerbault, P., Liebert, A., Itan, Y., Powell, A., Currat, M., Burger, J., Swallow, D. and Thomas, M.G. 2011. Evolution of lactase persistence: an example of human niche construction. Philosophical Transactions of the Royal Society B: Biological Sciences. 366
, pp. 863-877.

2009

Impact of selection and demography on the diffusion of lactase persistence. (2009)
Gerbault, P., Moret, C., Currat, M. and Sanchez-Mazas, A. 2009. Impact of selection and demography on the diffusion of lactase persistence. PLoS One. 4 (7), p. e6369.

2015

Human evolutionary genetics (2015)
Gerbault, P. and Thomas, M.G. 2015. Human evolutionary genetics. in: International encyclopedia of the social & behavioral sciences (second edition) Elsevier. pp. 289-296

2014

Lactose malabsorption and nutrition (2014)
Gerbault, P., Liebert, A., Swallow, D.M. and Thomas, M.G. 2014. Lactose malabsorption and nutrition. in: Lomer, M. (ed.) Advanced Nutrition and Dietetics in Gastroenterology Wiley. pp. 202-209

2012

Domestication and migrations: Using mitochondrial DNA to infer domestication processes of goats and horses (2012)
Gerbault, P., Leonardi, M., Powell, A., Weber, C., Benecke, N., Burger, J. and Thomas, M.G. 2012. Domestication and migrations: Using mitochondrial DNA to infer domestication processes of goats and horses. in: Kaiser, E., Burger, J. and Schier, Wo (ed.) Population Dynamics in Prehistory and Early History: New Approaches Using Stable Isotopes and Genetics. Berlin, Germany De Grutyer. pp. 17-30
Inferring processes of Neolithic gene-culture co-evolution using genetic and archaeological data: The case of lactase persistence and dairying (2012)
Gerbault, P., Bollongino, R., Burger, J. and Thomas, M.G. 2012. Inferring processes of Neolithic gene-culture co-evolution using genetic and archaeological data: The case of lactase persistence and dairying. in: Colledge, S., Conolly, J., Dobney, K., Manning, K. and Shennan, S. (ed.) The Origins and Spread of Domestic Animals in Southwest Asia and Europe Walnut Creek, CA Left Coast Press. pp. 37-48

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